Transistor‐Based Biosensors: From Theory to Real Devices

Dear Colleagues,

We invite you to contribute to this Special Issue concerning  transistor‐based biosensors. Electron biosensors based on field-effect transistors (FETs) are universal, high-sensitivity, real-time, label-free platforms for biomolecular detection. First of all, these sensors are requested in the field of medical diagnostics for point‐of-care testing of various analytes (DNA, RNA, proteins, and others). Different types of transistors made of different materials To date, the development of such devices has reached the stage of commercialization. Reproducibility and stability of the sensor response are the key issues hindering their large-scale deployment/application. The increase in sensitivity is an acute issue, since most disease markers are low-copy and their content in human biofluids, especially at the early stage of diseases, is at the femto- and subfemtomolar level. The topics of this Special Issue allow you to present various approaches aimed (1) to reduce the limit of detection and increase the linear range of target detection for early diagnosis and treatment prediction of diseases, and (2) to increase the stable device performance. Topics may include, but are not limited to:

• Target delivery of analytes to the sensor surface;
• Minimizing non-specific adsorption;
• Overcoming Debye length limitations for biomolecule sensing;
• Surface functionalization and characterization;
• Signal-enhanced methods;
• Comparison of perfection of sensors on the basis of different materials.

Original experimental and theoretical papers and reviews are welcome.

Dr. Olga Victorovna Naumova
Dr. Elena Dmitrienko
Guest Editors

Manuscript Submission Information

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