Dear Colleagues,

Point-of-care devices are unique diagnostic technologies that provide the potential for rapid biomarker detection and monitoring of medical conditions, thereby bypassing the demand for high-cost clinical laboratory facilities in many cases. Bioelectric sensors are suitable for use in handheld diagnostic devices due to the integrated electronic detection instrumentation and low requirement for processing reagents. Nowadays, bioelectric impedance sensing is widely used in tissue analysis such as body composition monitoring, however, its use in point-of-care patient testing is yet to be widely adopted.

Bioelectric signals correspond to an important set of cell growth and proliferation regulation mechanisms. Μore and more findings suggest the existence of specific cell-associated impedance patterns as a means of each cell response to a specific set of current frequencies and the alterations between normal and pathological cell-specific frequency levels. As more powerful, yet feasible and often portable instrumentation becomes commercially available, bioimpedance spectroscopy is gradually becoming a favorable tool for non-invasive, reagentless monitoring of cell physiology in response to a literally inexhaustible array of environmental stimular and experimental treatments. At the same time, bioelectric profiling is being rapidly established as a biocompatible, affordable and miniaturized tool for a number of applications, including in vitro toxicity, signal transduction, real-time medical diagnostics, as wells as hallmark for early detection of diseases.

The aim of this Special Issue is to focus on the most recent advances and developments of biosensors in the field of bioelectric impedance sensing. Suggested topics are bioelectric sensors for single cell analysis, impedimetric biosensors, wireless biological electronic sensors, and implantable autonomous bioelectric micro- and nano-sensors. In addition, approaches providing a point-of-care/portable and wireless instrumentation, high throughput analytical capacity, and intelligent bioelectric impedance sensing platforms are also welcome.

Research papers, short communications, and reviews are all welcome.

Prof. Dr. Spyridon Kintzios
Dr. Sofia Mavrikou
Guest Editors

Manuscript Submission Information

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• Bioelectric
• Bioelectric profiling
• Biosensor
• Cell-based biosensors
• Organ-on-a-Chip
• Differentiation
• Morphogenesis
• Pharmacology research
• Impedimetric
• Impedance spectrometry
• Implantable
• Medical diagnostics
• Βioanalysis
• Single cell analysis
• Biomarker
• Toxicology