Cognitive Impairment in Neuropsychiatry

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Psychiatric Diseases".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1094

Special Issue Editor


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Guest Editor
Neuropsychology and Behavioral Neurology Unit, Division of Molecular and Cognitive Neuroscience, Department of Psychology, University of Basel, Birmannsgasse 8, 4055 Basel, Switzerland
Interests: multiple sclerosis; Parkinson’s disease; dementia; depression; stress and cognition
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Special Issue Information

Dear Colleagues,

Cognition can be defined as the ability of processing higher level information from different sensory inputs in order to cope with everyday demands. It generally refers to mental abilities, such as attention, memory, language and mental flexibility. Cognitive impairments may occur as a consequence of distinct brain damage, but they may also arise in the context of psychiatric disorders. By recognizing that both organic, i.e., brain-damage related as well as non-organic, i.e., psychiatric diseases share the same pathological substrate, namely neuronal, biochemical and (epi-)genetic mechanisms, the resulting dysfunctions are often declared as neuropsychiatric disturbances. The range and severity of cognitive disturbances varies between psychiatric disorders, and in some conditions, cognitive alterations may even be recognized as prodromal markers.

This Special Issue aims to collate a wide array of clinical and laboratory research, including original high-quality papers, reviews as well as single case studies that elucidate the pathophysiological underpinnings, diagnosis, treatment, and the psychosocial consequences of neuropsychiatric conditions.

Prof. Dr. Pasquale Calabrese
Guest Editor

Manuscript Submission Information

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Keywords

  • cognition impairment
  • multiple sclerosis
  • Parkinson’s disease
  • dementia
  • depression
  • stress and cognition
  • neuropsychiatric conditions

Published Papers (1 paper)

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Review

25 pages, 594 KiB  
Review
The Effect of Antipsychotics on Cognition in Schizophrenia—A Current Narrative Review
by Petru Fabian Lungu, Corina Miruna Lungu, Alin Ciobica, Ioana Miruna Balmus, Raluca Vitalaru, Ioannis Mavroudis, Romeo Dobrin, Mirela Cimpeanu and Irina Luciana Gurzu
Brain Sci. 2024, 14(4), 359; https://doi.org/10.3390/brainsci14040359 - 03 Apr 2024
Viewed by 848
Abstract
The majority of schizophrenia-affected individuals display deficiencies in multiple cognitive domains such as attention, working memory, long-term memory, and learning, deficiencies that are stable throughout the disease. The purpose of this narrative review was to examine the effect of antipsychotics on several cognitive [...] Read more.
The majority of schizophrenia-affected individuals display deficiencies in multiple cognitive domains such as attention, working memory, long-term memory, and learning, deficiencies that are stable throughout the disease. The purpose of this narrative review was to examine the effect of antipsychotics on several cognitive domains affected by schizophrenia. Methods: We searched MEDLINE, Elsevier, Scopus, and DOAJ databases for randomized controlled trials and other studies investigating the effects of typical and atypical antipsychotics on cognition in patients with schizophrenia in studies conducted in the last decade. Results: The majority of studies included in this review showed that antipsychotics (especially SGAs) have positive effects on both cognition and general psychopathology of schizophrenia. We mention that treatment with antipsychotic substances represents an ongoing effort of the researchers, who are constantly searching for the best approach to meet the mental health needs of schizophrenia patients. Conclusions: Even with those positive results, it should be noted that more studies are needed in order to fully observe the various effects of certain antipsychotic substances on cognition. Full article
(This article belongs to the Special Issue Cognitive Impairment in Neuropsychiatry)
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