Recent Developments in the Role of Enteroendocrine Cells in Gastrointestinal and Non-gastrointestinal Disorders

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 30 June 2025 | Viewed by 640

Special Issue Editors


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Guest Editor
Department of Internal Medicine, Faculty of Medicine, Al-Balqa Applied University, Salt, Jordan
Interests: enteroendocrine cells; microbiota; gut hormones; intestinal ultrasound; endoscopic ultrasound; IBS; IBD

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Guest Editor
Medisinsk Undersøkelse, Haukeland University Hospital, 5021 Bergen, Norway
Interests: colorectal cancer; inflammatory bowel disease; sonography; irritable bowel syndrome (IBS); gastroenterology

Special Issue Information

Dear Colleagues,

Enteroendocrine cells are a specialized type of cells that line the gastrointestinal tract. They contain specialized microvilli that can sense luminal contents such as micronutrients, microbiota, and short-chain fatty acids, and secrete gut hormones to control the functions of the gastrointestinal tract. These gut hormones affect other organs, and are thus used as drugs for the treatment of diseases outside of the gastrointestinal tract.

Research during the last decade has found that enteroendocrine cells play an important role in several gastrointestinal disorders, such as irritable bowel syndrome and microscopic colitis, as well as in non-gastrointestinal disorders such as diabetes, obesity, and Parkinson’s disease. Several methods have been used to investigate the disturbances of these cells, some of which include disturbances in cellular quantity, function, stem origin, and genetics.  

However, more research is needed to elaborate the role of these specialized cells in gastrointestinal and non-gastrointestinal disorders. In this Special Issue, we aim to highlight such research. We would like to welcome all researchers to submit their articles to this Special Issue concerning recent developments in the role of enteroendocrine cells in gastrointestinal and non-gastrointestinal disorders.

Dr. Tarek Mazzawi
Prof. Dr. Trygve Hausken
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • enteroendocrine
  • stem cells
  • quantification
  • transcriptome
  • immunohistochemistry
  • gut hormones
  • obesity
  • Parkinson’s disease
  • diabetes
  • IBD

Published Papers

This special issue is now open for submission.
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