Emerging Prospects of Biogenesis and Function of Extracellular Vesicle in Cancer Cells
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 176
Special Issue Editor
Interests: vascular dysfunction; inflammation-associated disease; cancer; extracellular vesicle (EV) subpopulations; BBB disruption; cell migration; cell adhesion; EV omics; biosensor (EV on-chip); bio(nano)material
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
According to the World Health Organization (WHO), in 2020, there were an estimated 9.96 million cancer-related deaths globally. The intricate interplay among endothelial cells, immune cells, and cancer cells, along with the process of angiogenesis, is the key to cancer progression and ultimately influences therapeutic outcomes in cancer treatment.
The discovery of extracellular vesicles (EVs) has recently revolutionized the understanding of intercellular communication in cancer. EVs are submicron-sized membranous biological vesicles that are involved in the exchange of a wide range of functional biomolecules (lipid, protein, mRNA, and miRNA) between cells. An elevated concentration of EV has been reported in the blood of patients suffering from cancer. Owing to their non-invasive nature, EVs offer a potential alternative to traditional tissue biopsies. In addition, increasing attention has been given to the translational potential of EVs as a reliable liquid biopsy for the diagnosis and monitoring of several diseases, including cancer.
In this Special Issue of Cells, I invite you to contribute original research articles, reviews, or shorter perspective articles on all aspects related to the theme of “Emerging Prospects of Biogenesis and Function of Extracellular Vesicles in Cancer Cells”. Expert articles which focus on the following topics are highly welcome:
- Isolation and characterization of EV subpopulations in cancer;
- Cargo signature and functional integrity of EVs at the interplay between endothelial cells, immune cells, and cancer cells;
- EV biogenesis and release;
- Cellular and molecular mechanisms of EV in cancer;
- EV cargo and biomarker discovery for cancer;
- EVs as therapeutic tools;
- EC and drug resistance;
- EV as a liquid biopsy in cancer.
Dr. Baharak Hosseinkhani
Guest Editor
Manuscript Submission Information
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Keywords
- cancer
- extracellular vesicles
- biomarker
- liquid biopsy
