Mitochondria Meets Oxidative Stress
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Mitochondria".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 231
Special Issue Editors
Interests: mitochondria; bioenergetics; diabetes; medicinal plants; functional foods
Interests: mitochondria; oxidative stress; reactive oxygen species (ROS); cellular respiration; antioxidant defense
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mitochondria are crucial in generating cell energy, often celebrated as the cellular powerhouse, despite triggering numerous other critical functions in cell metabolism. However, a delicate equilibrium is disrupted when these tiny organelles face oxidative stress. As both a source and target of reactive oxygen species (ROS), mitochondria become central figures in the intricate dance with oxidative stress. Although ROS are natural byproducts of mitochondrial respiration, elevated levels can damage cellular components. Mitochondria possess sophisticated defense mechanisms to counteract oxidative stress, employing antioxidants and repair systems. The dysfunction of mitochondria due to oxidative stress is associated with various chronical noncommunicable diseases, including neurodegenerative disorders, cardiovascular issues, and ageing. Grasping this intersection is essential for unravelling the complex cellular health and pathology network and aiming to decipher the molecular intricacies that could lead to innovative therapeutic strategies. These strategies may encompass antioxidants, therapies specifically targeting mitochondria, and lifestyle interventions to alleviate oxidative stress and enhance mitochondrial function, thereby mitigating its impact on cellular function and overall health.
Dr. Fernanda M. Ferreira
Dr. Francisco Peixoto
Guest Editors
Manuscript Submission Information
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Keywords
- mitochondria
- oxidative stress
- reactive oxygen species (ROS)
- cellular respiration
- antioxidant defense
- ageing
