Maternal–Fetal Health: Helping Children Grow

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neonatology".

Deadline for manuscript submissions: 10 March 2025 | Viewed by 2533

Special Issue Editor


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Guest Editor
Meir Medical Center, Kfar Saba, Israel
Interests: brachial plexopathy; cleft lip and palate; clubfoot; corpus callosum agenesis; endometritis; neonatal sepsis; placental insufficiency

Special Issue Information

Dear Colleagues,

Prenatal diagnosis has been a staple in the field of maternal–fetal medicine for many years. New tools for ultrasound diagnosis, new screening strategies with which to identify serious diseases such as pre-eclampsia, risk of premature birth, and fetal anomalies, and the implementation of various preventive measures are among the latest achievements aimed at safeguarding maternal health and reducing fetal and neonatal morbidity and mortality.

This Special Issue will highlight recent advances in maternal–fetal medicine, including new approaches to fetal genetics and prenatal diagnosis and screening. Special attention will be paid to topics such as placental insufficiency, fetal malformation, fetal dysplasia, and genetic abnormalities.

Original research articles, systematic evaluations, analyses, and case-based comments are welcome. I look forward to receiving your contributions.

Dr. Ofer Markovitch
Guest Editor

Manuscript Submission Information

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Keywords

  • corpus callosum agenesis
  • clubfoot
  • cleft lip and palate
  • placental insufficiency
  • prenatal diagnosis
  • prenatal ultrasound
  • polyhydramnion
  • olygohydramnion
  • fetal growth restriction
  • macrosomia
  • CMA abnormalities

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Published Papers (1 paper)

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Research

10 pages, 449 KiB  
Article
The Association of Prenatal Antibiotic Use with Attention Deficit and Autism Spectrum Disorders: A Nationwide Cohort Study
by Yu-Chun Lin, Ching-Heng Lin and Ming-Chih Lin
Children 2023, 10(7), 1128; https://doi.org/10.3390/children10071128 - 29 Jun 2023
Cited by 3 | Viewed by 2224
Abstract
(1) Background: Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are common cognitive and behavioral disorders. Antibiotics are widely used in pregnant women and their newborns. The objective of this study was to examine the potential association between prenatal exposure to [...] Read more.
(1) Background: Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are common cognitive and behavioral disorders. Antibiotics are widely used in pregnant women and their newborns. The objective of this study was to examine the potential association between prenatal exposure to antibiotics and the risk of ADHD and ASD in childhood from a nationwide perspective. (2) Methods: The Taiwan National Health Insurance Research Database (NHIRD) was used as the primary data source. This nationwide cohort study included only first-time pregnancies. A total of 906,942 infants were enrolled. All infants were followed up for at least 6 years. The Cox regression model was applied for covariate control. (3) Results: Prenatal exposure to antibiotics was found to significantly increase the cumulative incidence of ADHD while having only a borderline effect on the cumulative incidence of ASD. Exposure to antibiotics during any of the three different gestational age ranges significantly increased the cumulative risk. However, only exposure after 34 weeks of gestation had a significant impact on the occurrence of ASD. The study also revealed a dose-dependent effect on the occurrence of ADHD but no effect on the occurrence of ASD. (4) Conclusions: This study suggests that prenatal exposure to antibiotics may increase the risk of developing ADHD and ASD later in life. Full article
(This article belongs to the Special Issue Maternal–Fetal Health: Helping Children Grow)
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