Fabrication and Biomedical Applications of Multifunctional Bio-Interfaces
A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Bioactive Coatings and Biointerfaces".
Deadline for manuscript submissions: closed (28 April 2024) | Viewed by 2200
Special Issue Editor
Special Issue Information
Dear Colleagues,
Biomaterials and biomaterial coatings play a crucial role in various biomedical applications, ranging from enhanced osseointegration with inert ceramic coatings to the prevention of thrombosis via heparin-eluting stents. These coatings’ success or failure depends on factors such as the surface roughness and chemical functional groups, which greatly impact the bio-interface and its interactions. Understanding these effects is essential to the optimization of the bio-interface and its interactions; for example, reducing stem cell differentiation or increasing osteointegration via the surface roughness.
The functionalization of materials with specific chemistries (e.g., amines, phosphates, etc.) or biomimetic sequences enables the addition of beneficial moieties that may match the physical requirements of the application but not the biochemical. This has been observed in the improved performance of biomedical devices employing immobilized proteins and peptides on the surface. Omniphobic surfaces also show promise in reducing cellular establishment and thrombogenesis in implanted devices, as well as in enabling the formation of 3D cell spheroids in microfluidic and culturing environments.
Current research on functionalizing implantable devices has made significant advances, but optimal integration occurs when multiple functionalities are simultaneously expressed at the interface and surface. Therefore, the future of biomaterials and bio-interfaces lies in maximizing their multi-functionality. Techniques that can be effectively translated from the lab to industry have the incredible potential to improve the health outcomes of countless individuals.
This Special Issue will seek to explore the various methods employed to fabricate functional biomaterials and bio-interfaces, and their applications in regenerative tissue engineering and biomedical devices (e.g., bone and dental implants). In this Special Issue, original research articles and reviews are welcome. Research areas may include, but are not limited to, the following:
- Intriguing fabrication methodologies and recent developments in biomaterials and bio-interfaces;
- Multi-functionality of biomedicine, and bio-interfacing and devices;
- Investigations into the interaction of the material–biological environment and its effects on in vitro/in vivo research;
- Applications of materials for tissue engineering, including orthopedics, dentistry, etc.
Dr. Callum Arthur Charles Stewart
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biomaterials and bio-interfaces
- multifunctional biomaterials
- tissue engineering
- bone and dental regeneration
