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Calcium Phosphate and Bioglass Materials for Bone Implant Applications
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Calcium Phosphate and Bioglass Materials for Bone Implant Applications

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Bioactive Coatings and Biointerfaces".

Deadline for manuscript submissions: 10 June 2024 | Viewed by 18042

Special Issue Editors

Dr. Richard Drevet

E-Mail Website
Guest Editor
Department of Plasma Physics and Technology, Masaryk University, Brno, Czech Republic
Interests: coatings and films; characterization and testing; materials science; biomaterials
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Hicham Benhayoune

E-Mail Website
Guest Editor
Institut de Thermique, Mécanique et Matériaux (ITheMM), Université de Reims Champagne-Ardenne (URCA), Reims, France
Interests: electrochemical deposition; electrophoretic deposition; biomaterials; prosthetic coatings; calcium phosphates; bioactive glasses; bone substitutes; electron microscopy; X-ray microanalysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

At present, the academic and industrial research efforts to improve the lifespan of bone implant materials are growing more and more due to an increasing worldwide clinical demand in skeletal repair, particularly for orthopaedic and dental surgeries. To reach this objective, many research labs focus their works on improving the osseointegration of bone implants by modifying the surface of prosthetic alloys with bioactive coatings made of calcium phosphate or bioglass. These coatings support the bone cells’ growth at the surface of the implant, promoting the formation of an intimate link with the surrounding bone tissues.

Several methods can be used to synthesize bioactive coatings on prosthetic alloys such as plasma spraying, magnetron sputtering, pulsed laser-deposition, electrophoretic deposition or electrodeposition. Particularly, the low-temperature processes can be used to add organic components (polymers, proteins, drugs, etc.) inside the prosthetic coatings in order to enhance the biological and mechanical properties of the biomaterials.

In that framework, this Special Issue aims at presenting the latest developments in this field.

In particular, the topics of interest include but are not limited to:

  • Calcium phosphate coatings for bone implant applications;
  • Bioglass coatings for bone implant applications;
  • Functionalization of biomaterials;
  • Bone implants with enhanced biological properties;
  • Bone implants with enhanced mechanical properties.

Dr. Richard Drevet
Prof. Dr. Hicham Benhayoune
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • calcium phosphate
  • bioglass
  • bone implant
  • functionalization of biomaterials
  • biomaterials with enhanced properties

Published Papers (5 papers)

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Editorial

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3 pages, 212 KiB  
Editorial
Calcium Phosphates and Bioactive Glasses for Bone Implant Applications
by Richard Drevet, Joël Fauré and Hicham Benhayoune
Coatings 2023, 13(7), 1217; https://doi.org/10.3390/coatings13071217 - 07 Jul 2023
Viewed by 1050
Abstract
The worldwide clinical demand for skeletal repair is constantly increasing due to the aging of the population [...] Full article
(This article belongs to the Special Issue Calcium Phosphate and Bioglass Materials for Bone Implant Applications)

Review

Jump to: Editorial

27 pages, 6140 KiB  
Review
Bioactive Calcium Phosphate Coatings for Bone Implant Applications: A Review
by Richard Drevet, Joël Fauré and Hicham Benhayoune
Coatings 2023, 13(6), 1091; https://doi.org/10.3390/coatings13061091 - 13 Jun 2023
Cited by 9 | Viewed by 2939
Abstract
This review deals with the design of bioactive calcium phosphate coatings deposited on metallic substrates to produce bone implants. The bioceramic coating properties are used to create a strong bonding between the bone implants and the surrounding bone tissue. They provide a fast [...] Read more.
This review deals with the design of bioactive calcium phosphate coatings deposited on metallic substrates to produce bone implants. The bioceramic coating properties are used to create a strong bonding between the bone implants and the surrounding bone tissue. They provide a fast response after implantation and increase the lifespan of the implant in the body environment. The first part of the article describes the different compounds belonging to the calcium phosphate family and their main properties for applications in biomaterials science. The calcium-to-phosphorus atomic ratio (Ca/P)at. and the solubility (Ks) of these compounds define their behavior in a physiological environment. Hydroxyapatite is the gold standard among calcium phosphate materials, but other chemical compositions/stoichiometries have also been studied for their interesting properties. The second part reviews the most common deposition processes to produce bioactive calcium phosphate coatings for bone implant applications. The last part describes key physicochemical properties of calcium phosphate coatings and their impact on the bioactivity and performance of bone implants in a physiological environment. Full article
(This article belongs to the Special Issue Calcium Phosphate and Bioglass Materials for Bone Implant Applications)
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15 pages, 1338 KiB  
Review
Bioactive Glass Applications in Different Periodontal Lesions: A Narrative Review
by Muhammad Saad Shaikh, Muhammad Amber Fareed and Muhammad Sohail Zafar
Coatings 2023, 13(4), 716; https://doi.org/10.3390/coatings13040716 - 31 Mar 2023
Cited by 4 | Viewed by 1878
Abstract
Tissue engineering in the orofacial region with bioactive components by the activation of immune complexes or other proteins is the current focus of biomaterials research. Consequently, natural ground materials and tissue components are being created. Bioactive glass is one of the most promising [...] Read more.
Tissue engineering in the orofacial region with bioactive components by the activation of immune complexes or other proteins is the current focus of biomaterials research. Consequently, natural ground materials and tissue components are being created. Bioactive glass is one of the most promising biomaterials and has bioactive properties making it suited for a range of different clinical dental applications, including the regeneration of hard tissues in the craniofacial region. This narrative review provides a summary of the favorable properties and recent applications of bioactive glass materials for the management of periodontal lesions. Bioactive glass mimics natural calcified tissues in terms of composition and has a bioactive role in bone regeneration. The present review concluded that bioactive glass materials have a promising potential for various periodontal applications including the repair of infrabony defects, gingival recession, furcation defects, and guided tissue regeneration. However, further in vivo studies and clinical trials are warranted to advance and validate the potential of bioactive glass for periodontal applications and translate its usage in dental clinics for periodontology. Full article
(This article belongs to the Special Issue Calcium Phosphate and Bioglass Materials for Bone Implant Applications)
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24 pages, 5725 KiB  
Review
Electrodeposition of Calcium Phosphate Coatings on Metallic Substrates for Bone Implant Applications: A Review
by Richard Drevet and Hicham Benhayoune
Coatings 2022, 12(4), 539; https://doi.org/10.3390/coatings12040539 - 17 Apr 2022
Cited by 23 | Viewed by 4934
Abstract
This review summaries more than three decades of scientific knowledge on electrodeposition of calcium phosphate coatings. This low-temperature process aims to make the surface of metallic bone implants bioactive within a physiological environment. The first part of the review describes the reaction mechanisms [...] Read more.
This review summaries more than three decades of scientific knowledge on electrodeposition of calcium phosphate coatings. This low-temperature process aims to make the surface of metallic bone implants bioactive within a physiological environment. The first part of the review describes the reaction mechanisms that lead to the synthesis of a bioactive coating. Electrodeposition occurs in three consecutive steps that involve electrochemical reactions, pH modification, and precipitation of the calcium phosphate coating. However, the process also produces undesired dihydrogen bubbles during the deposition because of the reduction of water, the solvent of the electrolyte solution. To prevent the production of large amounts of dihydrogen bubbles, the current density value is limited during deposition. To circumvent this issue, the use of pulsed current has been proposed in recent years to replace the traditional direct current. Thanks to breaking times, dihydrogen bubbles can regularly escape from the surface of the implant, and the deposition of the calcium phosphate coating is less disturbed by the accumulation of bubbles. In addition, the pulsed current has a positive impact on the chemical composition, morphology, roughness, and mechanical properties of the electrodeposited calcium phosphate coating. Finally, the review describes one of the most interesting properties of electrodeposition, i.e., the possibility of adding ionic substituents to the calcium phosphate crystal lattice to improve the biological performance of the bone implant. Several cations and anions are reviewed from the scientific literature with a description of their biological impact on the physiological environment. Full article
(This article belongs to the Special Issue Calcium Phosphate and Bioglass Materials for Bone Implant Applications)
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14 pages, 3491 KiB  
Review
Structural Changes of Hydroxylapatite during Plasma Spraying: Raman and NMR Spectroscopy Results
by Robert B. Heimann
Coatings 2021, 11(8), 987; https://doi.org/10.3390/coatings11080987 - 19 Aug 2021
Cited by 10 | Viewed by 2675
Abstract
Functional osseoconductive coatings based on hydroxylapatite (HAp) and applied preferentially by atmospheric plasma spraying to medical implant surfaces are a mainstay of modern implantology. During contact with the hot plasma jet, HAp particles melt incongruently and undergo complex dehydration and decomposition reactions that [...] Read more.
Functional osseoconductive coatings based on hydroxylapatite (HAp) and applied preferentially by atmospheric plasma spraying to medical implant surfaces are a mainstay of modern implantology. During contact with the hot plasma jet, HAp particles melt incongruently and undergo complex dehydration and decomposition reactions that alter their phase composition and crystallographic symmetry, and thus, the physical and biological properties of the coatings. Surface analytical methods such as laser-Raman and nuclear magnetic resonance (NMR) spectroscopies are useful tools to assess the structural changes of HAp imposed by heat treatment during their flight along the hot plasma jet. In this contribution, the controversial information is highlighted on the existence or non-existence of oxyapatite, i.e., fully dehydrated HAp as a thermodynamically stable compound. Full article
(This article belongs to the Special Issue Calcium Phosphate and Bioglass Materials for Bone Implant Applications)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review. 

 

Planned Paper 1

Title: Optimization of Sono-Electrodeposition Process for Various Cations Incorpororation into Calcium-Deficient Hydroxyapatite Deposited on Carbon Fiber Cloth
Authors: Sylvie Bonnamy, Florian Olivier, et al.
Affiliation: Centre National de la Recherche Scientifique (CNRS), University Orléans, ICMN UMR 7374, F-45071 Orléans, France

 
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