Dear Colleagues,

Malignant tumours are among the most prevalent diseases worldwide. An early, correct and complete diagnosis of the initial disease or recurrence, followed by appropriate and personalized treatment, can significantly reduce mortality, physical morbidity and psychological distress in affected patients. For many tumour entities, pathology represents the diagnostic “gold standard” in order to reach the diagnosis, ensure staging, and predict prognosis or the response to treatment.

The Special Issue will be devoted to advances and best practice in diagnostic pathology for cancer evaluation. The topics broadly include, but are not limited to:

• Tissue investigation in cancer diagnostics and treatment regarding both the most common and infrequent tumours: cancers of the breast, lung, prostate, digestive tract, pancreas, liver and biliary system, as well as reproductive, endocrine or other. The authors should focus on histopathologic diagnostic protocols; the complementarity of histopathologic and molecular investigations in limited tissue material; differential diagnostics; molecular classifications and treatment-related molecular changes; the heterogeneity of tumours; as well as on the morphological analysis of the tumour microenvironment, angiogenesis, metabolism, stemness, and tumour-related inflammation;
• The problems and solutions in the morphological diagnostics of rare tumours;
• Digital pathology in tumour diagnostics;
• Molecular pathology in cancer diagnostics;
• Ancillary studies and the future of diagnostic tumour pathology: technological studies and advancements including the latest developments or optimized protocols for immunohistochemistry and/or in situ hybridisation; miRNA analysis; types and technologies of tissue microscopy; in vivo endoscopic optical microscopy; the correlation between tissue assessment and non-invasive diagnostics, etc.

Original articles and reviews are welcome. Interesting images are welcome as an attractive form of scientific article; however, these should be supplemented by a scientifically sound literature review ensuring a representative insight in the given pathology.

Prof. Dr. Ilze Štrumfa
Dr. Boriss Strumfs
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• breast cancer
• lung cancer
• colorectal cancer
• rare tumours
• pathology
• immunohistochemistry
• molecular pathology
• cancer microenvironment
• molecular classification
• cancer heterogeneity
• cancer stem cells