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Diagnostics
Special Issues
Diagnosis and Management of Nasal and Sinus Disorders
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Diagnosis and Management of Nasal and Sinus Disorders

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 4326

Special Issue Editors

Dr. Ta-Jen Lee

E-Mail Website
Guest Editor
Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan
Interests: endoscopic sinus surgery; sinonasal neoplasms; septoplasty; turbinoplasty; allergic rhinitis; empty nose syndrome; rhinoplasty
Special Issues, Collections and Topics in MDPI journals
Dr. Chia-Hsiang Fu

E-Mail Website
Co-Guest Editor
Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital, Taoyuan 33382, Taiwan
Interests: rhinology; ENT; endoscopic surgery; pediatric otolaryngology

Special Issue Information

Dear Colleagues, 

Nasal and sinus disorders, such as acute/chronic rhinosinusitis, nasal polyposis, allergic/non-allergic rhinitis, empty nose syndrome, etc., frequently cause physical and psychiatric illness. Despite the rapid progress of medicine, some sinonasal disorders remain complex and have a significant impact on the global economy in the modern era. Early detection and proper management of the sinonasal airway deserve further attention. Advances in timely diagnosis and proper management would provide practical information about precise prognosis and likely response to medical or surgical therapy and are therefore pivotal.

On account of the great advances in the molecular and pathophysiological understanding of complex sinonasal disorders, the relevance of advances for the diagnosis and management has attracted a great deal of attention. This Special Issue will address current advances in the diagnosis and management of sinonasal disorders.

Dr. Ta-Jen Lee
Dr. Chia-Hsiang Fu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

12 pages, 726 KiB  
Article
Blood Basophils Relevance in Chronic Rhinosinusitis with Aspirin-Exacerbated Respiratory Disease
by Giuseppe Brescia, Cristoforo Fabbris, Leonardo Calvanese, Luigia Bandolin, Barbara Pedruzzi, Valerio Maria Di Pasquale Fiasca, Silvia Marciani, Francesca Mularoni, Fabio Degli Esposti Pallotti, Michael Negrisolo, Giacomo Spinato, Anna Chiara Frigo and Gino Marioni
Diagnostics 2023, 13(11), 1920; https://doi.org/10.3390/diagnostics13111920 - 31 May 2023
Cited by 1 | Viewed by 1515
Abstract
Aspirin-exacerbated respiratory disease (AERD) is characterized by eosinophilic asthma, chronic rhinosinusitis with nasal polyps (CRSwNP) and intolerance to cyclooxygenase-1 inhibitors. Interest is emerging in studying the role of circulating inflammatory cells in CRSwNP pathogenesis and its course, as well as their potential use [...] Read more.
Aspirin-exacerbated respiratory disease (AERD) is characterized by eosinophilic asthma, chronic rhinosinusitis with nasal polyps (CRSwNP) and intolerance to cyclooxygenase-1 inhibitors. Interest is emerging in studying the role of circulating inflammatory cells in CRSwNP pathogenesis and its course, as well as their potential use for a patient-tailored approach. By releasing IL-4, basophils play a crucial role in activating the Th2-mediated response. The main aim of this study was to, first, investigate the level of the pre-operative blood basophils’ values, blood basophil/lymphocyte ratio (bBLR) and blood eosinophil-to-basophil ratio (bEBR) as predictors of recurrent polyps after endoscopic sinus surgery (ESS) in AERD patients. The secondary aim was to compare the blood basophil-related variables of the AERD series (study group) with those of a control group of 95 consecutive cases of histologically non-eosinophilic CRSwNP. The AERD group showed a higher recurrence rate than the control group (p < 0.0001). The pre-operative blood basophil count and pre-operative bEBR were higher in AERD patients than in the control group (p = 0.0364 and p = 0.0006, respectively). The results of this study support the hypothesis that polyps removal may contribute to reducing the inflammation and activation of basophils. Full article
(This article belongs to the Special Issue Diagnosis and Management of Nasal and Sinus Disorders)
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16 pages, 4277 KiB  
Article
The Anthropometric Measurement of Nasal Landmark Locations by Digital 2D Photogrammetry Using the Convolutional Neural Network
by Nguyen Minh Trieu and Nguyen Truong Thinh
Diagnostics 2023, 13(5), 891; https://doi.org/10.3390/diagnostics13050891 - 26 Feb 2023
Cited by 5 | Viewed by 2450
Abstract
Measuring and labeling human face landmarks are time-consuming jobs that are conducted by experts. Currently, the applications of the Convolutional Neural Network (CNN) for image segmentation and classification have made great progress. The nose is arguably one of the most attractive parts of [...] Read more.
Measuring and labeling human face landmarks are time-consuming jobs that are conducted by experts. Currently, the applications of the Convolutional Neural Network (CNN) for image segmentation and classification have made great progress. The nose is arguably one of the most attractive parts of the human face. Rhinoplasty surgery is increasingly performed in females and also in males since surgery can help to enhance patient satisfaction with the resulting perceived beautiful ratio following the neoclassical proportions. In this study, the CNN model is introduced to extract facial landmarks based on medical theories: it learns the landmarks and recognizes them based on feature extraction during training. The comparison between experiments has proved that the CNN model can detect landmarks depending on desired requirements. Anthropometric measurements are carried out by automatic measurement divided into three images with frontal, lateral, and mental views. Measurements are performed including 12 linear distances and 10 angles. The results of the study were evaluated as satisfactory with a normalized mean error (NME) of 1.05, an average error for linear measurements of 0.508 mm, and 0.498° for angle measurements. Through its results, this study proposed a low-cost automatic anthropometric measurement system with high accuracy and stability. Full article
(This article belongs to the Special Issue Diagnosis and Management of Nasal and Sinus Disorders)
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