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Diagnostics
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Ultrasound in Liver and Biliary Diseases
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Ultrasound in Liver and Biliary Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 4369

Special Issue Editors

Dr. Tudor Voicu Moga

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Guest Editor
1. Department of Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy, Piața Eftimie Murgu 2, 300041 Timișoara, Romania
2. Center of Advanced Research in Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Interests: ultrasound; elastography; hepatocellular carcinoma; liver cirrhosis; gastroenterology
Prof. Dr. Alina Popescu

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Guest Editor
1. Department of Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy, Piața Eftimie Murgu 2, 300041 Timișoara, Romania
2. Center of Advanced Research in Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Interests: liver cirrhosis; hepatitis; liver; medicine; hepatocellular carcinoma; elastography; gastroenterology; liver diseases; viral hepatitis; ultrasound; hepatology; liver biopsy; chronic hepatitis c; ultrasonography; cirrhosis; acoustics; microbubbles; fatty liver; liver failure; hepatitis c
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue on ultrasound in liver and biliary diseases aims to provide a comprehensive platform for researchers and experts to share their latest findings and advancements in this rapidly evolving field. With a focus on ultrasound imaging techniques, this Special Issue explores the diagnosis, management, and treatment of liver and biliary diseases.

The scope of this Special Issue encompasses a wide range of topics, including, but not limited to, the role of ultrasound in liver fibrosis, hepatocellular carcinoma, cholelithiasis, biliary obstruction, and liver transplantation. The integration of cutting-edge technologies, such as contrast-enhanced ultrasound and liver elastography, will also be explored individually or in an integrated multiparametric concept. Given the intricate anatomical and pathological interplay between the liver, biliary system, and pancreas, it's recognized that many conditions simultaneously involve all these structures. Therefore, while the primary emphasis of this special issue remains on Ultrasound in Liver and Biliary Disease, we encourage submissions addressing topics related to pancreatic ultrasound.

The purpose of this Special Issue is to foster collaboration among multidisciplinary experts, including gastroenterologists, internal medicine physicians, radiologists, hepatologists, surgeons, and researchers in related fields. By presenting high-quality scientific papers and sharing the latest research trends, this Special Issue aims to advance our understanding of ultrasound applications in liver and biliary diseases and facilitate the development of novel diagnostic and therapeutic strategies.

Potential authors are encouraged to contribute their expertise and contribute to the progress of this field, ultimately benefiting patients by improving diagnostic accuracy, guiding treatment decisions, and enhancing patient outcomes.

We look forward to your valuable contributions and the opportunity to advance the understanding and treatment of liver and biliary diseases.

Dr. Tudor Voicu Moga
Prof. Dr. Alina Popescu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ultrasound
  • liver and biliary diseases
  • ultrasound imaging
  • liver fibrosis
  • hepatocellular carcinoma
  • cholelithiasis
  • biliary obstruction
  • liver transplantation

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Published Papers (3 papers)

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Research

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12 pages, 512 KiB  
Article
Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices
by Anita Madir, Mislav Barisic Jaman, Marko Milosevic, Petra Dinjar Kujundžić and Ivica Grgurevic
Diagnostics 2024, 14(7), 743; https://doi.org/10.3390/diagnostics14070743 - 30 Mar 2024
Viewed by 972
Abstract
Spleen stiffness measurement (SSM) by transient elastography (TE) has been repeatedly demonstrated as the reliable way to rule out the presence of high-risk esophageal varices (HRV). We aimed to evaluate and compare novel vs. standard TE-SSM module performance in diagnosing HRV in patients [...] Read more.
Spleen stiffness measurement (SSM) by transient elastography (TE) has been repeatedly demonstrated as the reliable way to rule out the presence of high-risk esophageal varices (HRV). We aimed to evaluate and compare novel vs. standard TE-SSM module performance in diagnosing HRV in patients with compensated advanced chronic liver disease (cACLD). This retrospective study included patients with cACLD; blood data, upper digestive endoscopy performed within 3 months of TE, SSM@50Hz and SSM@100Hz were collected. Overall, 112 patients with cACLD were analyzed (75.9% males, average age of 66, 43.7% alcohol-related chronic liver disease, 22.3% metabolic-associated steatotic liver disease, 6.2% viral hepatitis). Reliable SSM was possible in 80.3% and 93.8% of patients by using SSM@50Hz and SSM@100Hz probe, respectively. At the cut-off 41.8 kPa and 40.9 kPa (Youden), SSM@50Hz and SSM@100Hz had AUROCs of 0.746 and 0.752, respectively, for diagnosing HRV (p = 0.71). At the respective cut-offs, sensitivities for HRV were 92.9% and 100%, resulting in misclassification rates of 7.1% and 0% by using SSM@50Hz and SSM@100Hz. SSM reliably excludes HRV in cACLD patients, with measurements below 41 kPa potentially avoiding EGD in around 50% of cases, with minimal risk of HRV omission. SSM@100Hz demonstrated less measurement failures and no HRV misclassification. Full article
(This article belongs to the Special Issue Ultrasound in Liver and Biliary Diseases)
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10 pages, 4159 KiB  
Article
Hepatic Artery Delineation on Ultrasound Volumes Comparing B-Flow and Color Doppler for Postoperative Monitoring of Pediatric Liver Transplants
by Elena Dammann, Leonhard Steinmeister, Michael Groth, Uta Herden, Lutz Fischer, Florian Brinkert, Jan Beime, Magdalini Tozakidou, Peter Bannas and Jochen Herrmann
Diagnostics 2024, 14(6), 617; https://doi.org/10.3390/diagnostics14060617 - 14 Mar 2024
Viewed by 939
Abstract
(1) Background: Accurate hepatic artery (HA) depiction following pediatric liver transplantation (LT) is essential for graft surveillance but challenging on ultrasound (US). This study assesses if improved HA delineation can be achieved by recording two-dimensional US volumes in Color Doppler (CD) and B-flow [...] Read more.
(1) Background: Accurate hepatic artery (HA) depiction following pediatric liver transplantation (LT) is essential for graft surveillance but challenging on ultrasound (US). This study assesses if improved HA delineation can be achieved by recording two-dimensional US volumes in Color Doppler (CD) and B-flow technique. (2) Methods: Of 42 consecutive LT, 37 cases were included, and HA delineation was retrospectively rated using a four-point score (0 = HA not detectable, 3 = HA fully detectable, separable from portal vein) within 48 h post-LT (U1) and before discharge (U2). (3) Results: Adding B-flow compared with CD alone showed superior results at neohilar (U1: 2.2 ± 1.0 vs. 1.1 ± 0.8, p < 0.0001; U2: 2.5 ± 0.8 vs. 1.5 ± 0.9, p < 0.0001) and segmental levels (U1: 2.8 ± 0.6 vs. 0.6 ± 0.8, p < 0.0001; U2: 2.8 ± 0.6 vs. 0.7 ± 0.5, p < 0.0001). (4) Conclusions: Standardized US volume recordings combining B-flow and CD can effectively delineate the HA along its vascular course in pediatric LT. The technique should be further evaluated as a standard monitoring instrument to rule out vascular complications after LT. Full article
(This article belongs to the Special Issue Ultrasound in Liver and Biliary Diseases)
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Review

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22 pages, 11964 KiB  
Review
Ultrasound-Guided Interventions in the Biliary System
by Thomas Müller and Barbara Braden
Diagnostics 2024, 14(4), 403; https://doi.org/10.3390/diagnostics14040403 - 12 Feb 2024
Viewed by 1868
Abstract
Ultrasound guidance in biliary interventions has become the standard tool to facilitate percutaneous biliary drainage as well as percutaneous gall bladder drainage. Monitoring of the needle tip whilst penetrating the tissue in real time using ultrasound allows precise manoeuvres and exact targeting without [...] Read more.
Ultrasound guidance in biliary interventions has become the standard tool to facilitate percutaneous biliary drainage as well as percutaneous gall bladder drainage. Monitoring of the needle tip whilst penetrating the tissue in real time using ultrasound allows precise manoeuvres and exact targeting without radiation exposure. Without the need for fluoroscopy, ultrasound-guided drainage procedures can be performed bedside as a sometimes life-saving procedure in patients with severe cholangitis/cholecystitis when they are critically ill in intensive care units and cannot be transported to a fluoroscopy suite. This article describes the current data background and guidelines and focuses on specific sonographic aspects of both the procedures of percutaneous biliary drainage and gallbladder drainage. Full article
(This article belongs to the Special Issue Ultrasound in Liver and Biliary Diseases)
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