Diagnosis of Hepatobiliary and Pancreatic Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 1742

Special Issue Editor


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Guest Editor
Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, 22, Gwanpyeong-ro 170 Beon-gil, Dongan-gu, Anyang 14068, Gyeonggi-do, Republic of Korea
Interests: gastric cancer; gastrointestinal disease

Special Issue Information

Dear Colleagues,

The special issue "Diagnosis of Hepatobiliary and Pancreatic Diseases" aims to provide an in-depth exploration of the latest advancements, research findings, and diagnostic approaches in the field of hepatobiliary and pancreatic diseases. These diseases encompass a wide range of conditions affecting the liver, bile ducts, gallbladder, and pancreas, presenting significant challenges in diagnosis and management. This special issue will focus on various diagnostic modalities, including imaging techniques, molecular diagnostics, and biomarkers, to improve the accuracy and timeliness of diagnosis.

This issue will cover topics such as the role of advanced imaging modalities like computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) in the diagnosis and staging of hepatobiliary and pancreatic diseases. Additionally, it will explore the utility of molecular diagnostics, including genetic and genomic approaches, in identifying disease-causing variants and predicting treatment response. The special issue will also emphasize the emerging field of biomarkers and their potential use in early detection, prognosis, and monitoring of disease progression. 

By compiling research articles, reviews, and case studies, this special issue will serve as a comprehensive resource for clinicians, researchers, and healthcare professionals involved in the diagnosis and management of hepatobiliary and pancreatic diseases. It aims to facilitate knowledge exchange, foster innovation in diagnostic approaches, and improve patient outcomes through early and accurate diagnosis. The special issue is expected to contribute to the advancement of diagnostic strategies and personalized care in hepatobiliary and pancreatic diseases.

Prof. Dr. Dong Woo Shin
Guest Editor

Manuscript Submission Information

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Keywords

  • hepatobiliary and pancreatic diseases
  • imaging techniques
  • molecular diagnostics
  • biomarkers

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Published Papers (2 papers)

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10 pages, 797 KiB  
Article
Predictive Models for Non-Alcoholic Fatty Liver Disease Diagnosis in Mexican Patients with Gallstone Disease: Sex-Specific Insights
by Nemry Rodríguez-Hernández, María-Luisa Lazo-de-la-Vega-Monroy, Yeniley Ruiz-Noa, Monica-del-Carmen Preciado-Puga, Juana-Rosalba Garcia-Ramirez, Benjamin Jordan-Perez, Serafin Garnelo-Cabañas and Lorena-del-Rocío Ibarra-Reynoso
Diagnostics 2024, 14(14), 1487; https://doi.org/10.3390/diagnostics14141487 - 11 Jul 2024
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Abstract
(1) Background: Evidence regarding Non-Alcoholic Fatty Liver Disease (NAFLD) diagnosis is limited in the context of patients with gallstone disease (GD). This study aimed to assess the predictive potential of conventional clinical and biochemical variables as combined models for diagnosing NAFLD in patients [...] Read more.
(1) Background: Evidence regarding Non-Alcoholic Fatty Liver Disease (NAFLD) diagnosis is limited in the context of patients with gallstone disease (GD). This study aimed to assess the predictive potential of conventional clinical and biochemical variables as combined models for diagnosing NAFLD in patients with GD. (2) Methods: A cross-sectional study including 239 patients with GD and NAFLD diagnosed by ultrasonography who underwent laparoscopic cholecystectomy and liver biopsy was conducted. Previous clinical indices were also determined. Predictive models for the presence of NAFLD stratified by biological sex were obtained through binary logistic regression and sensitivity analyses were performed. (3) Results: For women, the model included total cholesterol (TC), age and alanine aminotransferase (ALT) and showed an area under receiver operating characteristic curve (AUC) of 0.727 (p < 0.001), sensitivity of 0.831 and a specificity of 0.517. For men, the model included TC, body mass index (BMI) and aspartate aminotransferase (AST), had an AUC of 0.898 (p < 0.001), sensitivity of 0.917 and specificity of 0.818. In both sexes, the diagnostic performance of the designed equations was superior to the previous indices. (4) Conclusions: These models have the potential to offer valuable guidance to healthcare providers in clinical decision-making, enabling them to achieve optimal outcomes for each patient. Full article
(This article belongs to the Special Issue Diagnosis of Hepatobiliary and Pancreatic Diseases)
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3 pages, 401 KiB  
Interesting Images
Cholecystocutaneous Fistula
by Francisco Tustumi, Giane Prata da Costa Filha and Guilherme Carvalhal Gnipper Cirillo
Diagnostics 2024, 14(13), 1386; https://doi.org/10.3390/diagnostics14131386 - 29 Jun 2024
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Abstract
This image article presents an 88-year-old indigenous woman with a history of several episodes of abdominal pain, for which she went to numerous different hospitals in the countryside, was always treated with analgesics, and then discharged. After a long time, the patient eventually [...] Read more.
This image article presents an 88-year-old indigenous woman with a history of several episodes of abdominal pain, for which she went to numerous different hospitals in the countryside, was always treated with analgesics, and then discharged. After a long time, the patient eventually was evaluated with magnetic resonance imaging. The test revealed a displaced gallbladder with thickened walls, multiple stones, and a fistulous tract extending to the skin. This case underscores the significant challenges faced by patients in regions with limited healthcare access, highlighting the impact of delayed diagnosis and inadequate management on patient outcomes. Full article
(This article belongs to the Special Issue Diagnosis of Hepatobiliary and Pancreatic Diseases)
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