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Diagnostics
Special Issues
Diagnosis and Management of Soft Tissue and Bone Tumors
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Diagnosis and Management of Soft Tissue and Bone Tumors

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 2392

Special Issue Editors

Dr. Min Wook Joo

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea
Interests: osteosarcoma; metastasis; clinical oncology; cancer metastasis
Dr. Shintaro Iwata

E-Mail Website
Guest Editor
Department of Musculoskeletal Oncology and Rehabilitation, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
Interests: sarcoma; rare cancer; genomics; clinical trial
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

At present, it is challenging to properly manage some malignant and other aggressive bone tumors, and effective decision making is required during diagnosis and treatment. To find reliable answers, consensus meetings, clinical trials, and big data studies are currently being conducted, and many of the latest diagnostic and treatment techniques are being applied. Nevertheless, there are still many obstacles to overcome for such rare diseases. This Special Issue aims to present a collection of advanced studies on basic, translational, and all other clinically significant soft tissue and bone tumors. We welcome your contributions on, but not limited to, the following topics:

  • Aneurysmal bone cysts;
  • Giant cell tumor of bone;
  • Polyostotic fibrous dysplasia;
  • Langerhans cell histiocytosis;
  • Osteofibrous dysplasia;
  • Adamantinoma;
  • Atypical cartilaginous tumors;
  • Chondromyxofibroma;
  • Osteosarcoma;
  • Chondrosarcoma;
  • Ewing’s sarcoma;
  • Chordoma.

Dr. Min Wook Joo
Dr. Shintaro Iwata
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aneurysmal bone cyst
  • giant cell tumor of bone
  • polyostotic fibrous dysplasia
  • Langerhans cell histiocytosis
  • osteofibrous dysplasia
  • adamantinoma
  • atypical cartilaginous tumor
  • chondromyxofibroma
  • osteosarcoma
  • chondrosarcoma
  • Ewing’s sarcoma
  • chordoma

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Published Papers (2 papers)

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10 pages, 2144 KiB  
Article
Developmental Patterns and Risk Factors of Scoliosis After Hemipelvectomy for the Pelvic Bone Tumor
by Ryuto Tsuchiya, Shintaro Iwata, Suguru Fukushima, Shuhei Osaki, Koichi Ogura, Eisuke Kobayashi, Seiji Ohtori and Akira Kawai
Diagnostics 2024, 14(21), 2392; https://doi.org/10.3390/diagnostics14212392 - 27 Oct 2024
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Abstract
Background: Postoperative scoliosis is often seen after hemipelvectomy for malignancies involving the pelvic area, but the details remain unclear. The objectives were to investigate the development patterns and risk factors of scoliosis after hemipelvectomy. Methods: We retrospectively reviewed 30 patients who underwent hemipelvectomy [...] Read more.
Background: Postoperative scoliosis is often seen after hemipelvectomy for malignancies involving the pelvic area, but the details remain unclear. The objectives were to investigate the development patterns and risk factors of scoliosis after hemipelvectomy. Methods: We retrospectively reviewed 30 patients who underwent hemipelvectomy at our hospital between 1998 and 2020. The risk factors of scoliosis with a Cobb angle of ≥10° were investigated. Results: The postoperative Cobb angle significantly increased in all patients compared with the preoperative one (p < 0.001), and the change ratio of the Cobb angle was significantly higher during the first postoperative year than thereafter. The external hemipelvectomy (EH) group demonstrated a larger Cobb angle and a higher change ratio than the internal hemipelvectomy group. Nine patients developed scoliosis with a final Cobb angle of ≥10°, and the risk factors were EH (p = 0.017), P1+2+3+4 resection according to the Enneking classification (p = 0.005), iliac crest resection (p = 0.004), L5/S resection (p = 0.020), and no pelvic ring reconstruction after hemipelvectomy (p = 0.004). Conclusions: Approximately 30% of patients who underwent hemipelvectomy developed scoliosis with a Cobb angle of ≥10°, and this angle increased rapidly during the first postoperative year. Hence, careful follow-up of scoliosis is required after hemipelvectomy. Full article
(This article belongs to the Special Issue Diagnosis and Management of Soft Tissue and Bone Tumors)
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9 pages, 13179 KiB  
Case Report
Benign Notochordal Cell Tumours: Case Report and Literature Review
by Dagnija Grabovska, Ilze Strumfa, Janis Ositis, Inta Liepniece-Karele and Arturs Balodis
Diagnostics 2024, 14(13), 1330; https://doi.org/10.3390/diagnostics14131330 - 23 Jun 2024
Viewed by 897
Abstract
Background: Benign notochordal cell tumours (BNCTs) represent a rare entity within the spectrum of bone neoplasms, which typically arise in the axial skeleton. Although these tumours are often benign, their diagnosis and management pose significant challenges due to their histological similarity to more [...] Read more.
Background: Benign notochordal cell tumours (BNCTs) represent a rare entity within the spectrum of bone neoplasms, which typically arise in the axial skeleton. Although these tumours are often benign, their diagnosis and management pose significant challenges due to their histological similarity to more aggressive lesions, such as chordomas. Understanding of the clinical behaviour, diagnostic nuances, and optimal management strategies for BNCTs continues to evolve. Case Report: Benign notochordal cell tumours of the vertebra are usually asymptomatic and identified on imaging and should be distinguished from chordomas, which has a more aggressive clinical course. This report describes a 15-year-old girl with lumbosacral pain and a diagnosis of a benign notochordal cell tumour, which affects a large part of the S1 vertebra in the lumbar spine, highlighting the diagnostic challenges encountered, the role of radiological and histological investigations, and the ultimate determination of the benign nature of the tumour. Conclusions: This report highlights the approach taken for the diagnosis of a benign notochordal cell tumour of the vertebra and the importance of excluding differential diagnoses. By exploring the intricacies of this case, we contribute to the growing body of literature surrounding BNCTs, with the aim of improving clinical awareness and management strategies for this uncommon bone tumour. Full article
(This article belongs to the Special Issue Diagnosis and Management of Soft Tissue and Bone Tumors)
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