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Diagnostics
Special Issues
Diagnosis and Management of Perinatal Medicine
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Diagnosis and Management of Perinatal Medicine

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 1046

Special Issue Editor

Prof. Dr. Daisuke Tachibana

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan
Interests: maternal; fetus; management; diagnosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Perinatal medicine is a relatively new specialty. Antenatal fetal assessment, the management of labor, including electronic monitoring in normal women and asphyxial brain damage, etc., represent major topics. This Special Issue is dedicated to advancing the diagnosis and management of perinatal medicine. We welcome a diverse range of contributions, including reviews, original research articles, case reports, interesting images, and guidelines, all aiming to advance our understanding of perinatal medicine.

Prof. Dr. Daisuke Tachibana
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • perinatal medicine
  • diagnosis
  • prognosis
  • antenatal fetal assessment
  • management of labor
 

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Published Papers (2 papers)

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5 pages, 6922 KiB  
Interesting Images
Fetal Cortical Abnormalities Identified on Ultrasound
by Mara Rosner, Casey Reed, Aylin Tekes, Lindsey N. Goodman, Angie C. Jelin, Jena L. Miller, Michelle L. Kush, Ahmet A. Baschat, Lisa R. Sun, Jessica M. DeMay and Kristin Baranano
Diagnostics 2024, 14(21), 2371; https://doi.org/10.3390/diagnostics14212371 - 24 Oct 2024
Viewed by 288
Abstract
Normal neuronal cell differentiation and migration is critical to brain formation, is rapidly occurring as the fetal brain develops, and peaks at the time of the routine ultrasound anatomic survey. Abnormalities in cortical migration can signify an underlying genetic abnormality or other fetal [...] Read more.
Normal neuronal cell differentiation and migration is critical to brain formation, is rapidly occurring as the fetal brain develops, and peaks at the time of the routine ultrasound anatomic survey. Abnormalities in cortical migration can signify an underlying genetic abnormality or other fetal injury that can have a profound impact on future development. Although cortical migration peaks at 20–22 weeks, cortical migration abnormalities are rarely diagnosed at the time of the anatomic survey. We describe three cases of fetal cortical abnormalities in which prenatal ultrasound imaging was instrumental to making a prompt and accurate diagnosis in the mid-trimester and for guiding clinical counseling. Full article
(This article belongs to the Special Issue Diagnosis and Management of Perinatal Medicine)
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8 pages, 2276 KiB  
Case Report
Ductus Venosus Agenesis in Monochorionic Twin Pregnancies Complicated by Fetal Growth Restriction: When to Deliver?
by Eleonora Torcia, Alessandra Familiari, Elvira Passananti, Giulia di Marco, Federica Romanzi, Mariarita Trapani, Daniela Visconti, Antonio Lanzone and Elisa Bevilacqua
Diagnostics 2024, 14(19), 2147; https://doi.org/10.3390/diagnostics14192147 - 26 Sep 2024
Viewed by 459
Abstract
Introduction: The prevalence of ductus venosus agenesis (ADV) in singleton pregnancies ranges from 0.04% to 0.15%, while its prevalence in twins remains largely unknown. To our knowledge, in the literature, there is only a single case report of a monochorionic diamniotic (MCDA) pregnancy [...] Read more.
Introduction: The prevalence of ductus venosus agenesis (ADV) in singleton pregnancies ranges from 0.04% to 0.15%, while its prevalence in twins remains largely unknown. To our knowledge, in the literature, there is only a single case report of a monochorionic diamniotic (MCDA) pregnancy complicated by ADV. Fetuses with ADV are at increased risk for congenital cardiac disease, heart failure, and fetal growth restriction (FGR). Consequently, these pregnancies have a heightened risk of experiencing an adverse outcome, like stillbirth and neonatal or infant death. Closer antenatal monitoring is warranted when ADV is suspected. Currently, there are no guidelines regarding the standard of care in cases of ADV and no recommendations for the timing of delivery in either singleton or twin pregnancies. Cases: This study aims to provide a comprehensive overview of the management of twin pregnancies complicated by ADV, featuring two cases of MC twins with concurrent sFGR and ADV in one twin. Discussion: These pregnancies experienced completely different outcomes, underscoring the necessity for personalized management tailored to the specific risk factors present in each pregnancy. Typically, in MCDA pregnancies with severe sFGR (type II and III), delivery represents the most reasonable option when venous Doppler abnormalities are identified. However, the absence of the DV complicates the management and the process of decision-making regarding the timing of delivery in cases of sFGR and ADV. We emphasize that effective decision-making should be guided by the presence of additional risk factors, including velamentous insertion, significant estimated fetal weight discordance, and progressive deterioration of the Doppler over time. Conclusions: Our experience suggests that these factors are strongly correlated with poorer outcomes. Given this context, could it be acceptable, in the case of MC pregnancy complicated by severe sFGR and ADV, with worsening findings and additional risk factors (e.g., velamentous insertion, severe birth weight discrepancy), to anticipate the time of delivery starting from 30 weeks of gestational age? Full article
(This article belongs to the Special Issue Diagnosis and Management of Perinatal Medicine)
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