Urinary Tract Infections: Diagnosis and Management

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Diagnostic Microbiology and Infectious Disease".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 3542

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Guest Editor
School of Public Health, Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel
Interests: clinical utility; urinary tract infections; elderly, internal medicine; laboratory testing
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Special Issue Information

Dear Colleagues,

The purpose of this Special Issue is threefold. First, we will review various methods for urinalysis, including the more recently introduced automated technology. Second, we will discuss the clinical utility and disutility of various findings. Finally, we will discuss indications for testing. Original research articles, reviews, short communications, and interesting images are welcome, as well as either clinical or basic research.

Prof. Dr. Paul Froom
Guest Editor

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Published Papers (1 paper)

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Research

11 pages, 1190 KiB  
Article
Atypical Presentation of Bacteremic Urinary Tract Infection in Older Patients: Frequency and Prognostic Impact
by Caroline Laborde, Julien Bador, Arthur Hacquin, Jérémy Barben, Sophie Putot, Patrick Manckoundia and Alain Putot
Diagnostics 2021, 11(3), 523; https://doi.org/10.3390/diagnostics11030523 - 15 Mar 2021
Cited by 5 | Viewed by 2892
Abstract
In older patients, urinary tract infection (UTI) often has an atypical clinical presentation, making its diagnosis difficult. We aimed to describe the clinical presentation in older inpatients with UTI-related bacteremia and to determine the prognostic impact of atypical presentation. This cohort study included [...] Read more.
In older patients, urinary tract infection (UTI) often has an atypical clinical presentation, making its diagnosis difficult. We aimed to describe the clinical presentation in older inpatients with UTI-related bacteremia and to determine the prognostic impact of atypical presentation. This cohort study included all consecutive patients older than 75 years hospitalized in a university hospital in 2019 with a UTI-related gram-negative bacillus (GNB) bacteremia, defined by blood and urine cultures positive for the same GNB, and followed up for 90 days. Patients with typical symptoms of UTI were compared to patients with atypical forms. Among 3865 inpatients over 75 with GNB-positive urine culture over the inclusion period, 105 patients (2.7%) with bacteremic UTI were included (mean age 85.3 ± 5.9, 61.9% female). Among them, UTI symptoms were reported in only 38 patients (36.2%) and 44 patients (41.9%) had no fever on initial management. Initial diagnosis of UTI was made in only 58% of patient. Mortality at 90 days was 23.6%. After adjustment for confounders, hyperthermia (HR = 0.37; IC95 (0.14–0.97)) and early UTI diagnosis (HR = 0.35; IC95 (0.13–0.94)) were associated with lower mortality, while UTI symptoms were not associated with prognosis. In conclusion, only one third of older patients with UTI developing bacteremia had UTI symptoms. However, early UTI diagnosis was associated with better survival. Full article
(This article belongs to the Special Issue Urinary Tract Infections: Diagnosis and Management)
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