Clinical Diagnosis and Treatment of Mouth Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 13778

Special Issue Editor

Special Issue Information

Dear Colleagues,

Mouth diseases are currently being studied by both dentists and doctors as they are frequently linked to systemic diseases.

An early and accurate diagnosis is important for the treatment of more aggressive diseases. Treatment of mouth diseases can be pharmacological or surgical and can lead to partial loss of the jaw bones. Frequent diseases such as tooth decay and periodontal disease can also require complex treatments. This Special Issue aims to contribute to the correct diagnosis and treatment of mouth diseases, and we welcome submissions on, but not limited to, stomatitis, caries, periodontal disease, oncological diseases, temporomandibular joint pathologies, malocclusions, and all possible therapies.

Prof. Dr. Massimo Corsalini
Guest Editor

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Keywords

  • stomatitis
  • oral cancer
  • periodontal disease
  • malocclusions
  • TMJ diseases
  • post surgical defects
  • oral rehabilitation
  • dental prosthesis
  • caries
  • new materials in oral rehabilitation

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Published Papers (4 papers)

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9 pages, 940 KiB  
Communication
Impact of Maximum Tongue Pressure in Patients with Jaw Deformities Who Underwent Orthognathic Surgery
by Koichi Koizumi, Tomoaki Shintani, Yuki Yoshimi, Mirai Higaki, Ryo Kunimatsu, Yukio Yoshioka, Kazuhiro Tsuga, Kotaro Tanimoto, Hideki Shiba and Shigeaki Toratani
Diagnostics 2022, 12(2), 404; https://doi.org/10.3390/diagnostics12020404 - 4 Feb 2022
Cited by 6 | Viewed by 1916
Abstract
Malocclusion and morphological abnormalities of the jawbone often affect the stomatognathic function and long-term postoperative stability in patients with jaw deformities. There are few reports on the effect of maximum tongue pressure (MTP) in these patients. We investigated the relationship between the MTP [...] Read more.
Malocclusion and morphological abnormalities of the jawbone often affect the stomatognathic function and long-term postoperative stability in patients with jaw deformities. There are few reports on the effect of maximum tongue pressure (MTP) in these patients. We investigated the relationship between the MTP and jawbone morphology and the effect of the MTP on surgery in 42 patients with jaw deformity who underwent surgical orthodontic treatment at Hiroshima University Hospital. The MTP was measured using a tongue pressure measurement device; the average value was considered as the MTP. Based on the MTP measured before surgery, patients were classified into the high- or the low-MTP group. The clinical findings and results of the cephalometric analysis were compared. Posterior movement of the mandible in the high-MTP group was significantly lower than that in the low-MTP group. The ANB angle, overjet, and overbite in the high-MTP group were significantly smaller than those in the low-MTP group. On the other hand, there was no difference between the two groups in the measured values, indicating a labial inclination of the anterior teeth (U1 to SN, U1 to FH, IMPA, and FMIA). MTP has been suggested to affect mandibular prognathism in patients with jaw deformities. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)
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10 pages, 1379 KiB  
Article
Dental Disorders and Salivary Changes in Patients with Laryngopharyngeal Reflux
by Sabrina Casciaro, Matteo Gelardi, Rossana Giancaspro, Vitaliano Nicola Quaranta, Giuseppe Porro, Brigida Sterlicchio, Antonia Abbinante and Massimo Corsalini
Diagnostics 2022, 12(1), 153; https://doi.org/10.3390/diagnostics12010153 - 9 Jan 2022
Cited by 4 | Viewed by 1728
Abstract
Background: Laryngopharyngeal reflux (LPR) is a common inflammatory condition of the upper aerodigestive tract tissues related to the effects of gastroduodenal content reflux, characterized by a wide variety of clinical manifestations. The aim of our study was to evaluate the possible association between [...] Read more.
Background: Laryngopharyngeal reflux (LPR) is a common inflammatory condition of the upper aerodigestive tract tissues related to the effects of gastroduodenal content reflux, characterized by a wide variety of clinical manifestations. The aim of our study was to evaluate the possible association between dental disorders and LRP, focusing on the role of salivary changes. Methods: Patient’s dental status was evaluated according to Schiff Index Sensitivity Scale (SISS), Basic Erosive Wear Examination (BEWE) and Decayed, Missing, and Filled Teeth (DMFT) scores. Reflux-associated symptoms were assessed according to Reflux symptom index (RSI). A qualitative and quantitative examination of saliva was performed. Results: Patients suffering from LPR had a higher incidence of dental disorders, regardless the presence of salivary pepsin, and thus, statistically significant higher scores of RSI (p = 0.0001), SISS (p = 0.001), BEWE (p < 0.001) and VAS (p < 0.001). Moreover, they had lower salivary flow compared with healthy patients. Conclusions: The finding of demineralization and dental caries on intraoral evaluation must raise the suspicion of LRP. Reflux treatments should also be aimed at correcting salivary alterations, in order to preserve the buffering capacity and salivary pH, thus preventing mucosal and dental damage. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)
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8 pages, 2278 KiB  
Article
Evaluation of Depth of Invasion and Tumor Thickness as a Prognostic Factor for Early-Stage Oral Squamous Cell Carcinoma: A Retrospective Study
by You-Jung Lee, Tae-Geon Kwon, Jin-Wook Kim, Sung-Tak Lee, Su-Hyung Hong and So-Young Choi
Diagnostics 2022, 12(1), 20; https://doi.org/10.3390/diagnostics12010020 - 23 Dec 2021
Cited by 7 | Viewed by 6897
Abstract
The aim of this study was to compare the effect of using depth of invasion (DOI) versus tumor thickness (TT) as a prognostic factor for early-stage oral squamous cell carcinoma (OSCC). A total of 57 patients with early-stage OSCC treated surgically from 2009 [...] Read more.
The aim of this study was to compare the effect of using depth of invasion (DOI) versus tumor thickness (TT) as a prognostic factor for early-stage oral squamous cell carcinoma (OSCC). A total of 57 patients with early-stage OSCC treated surgically from 2009 to 2014 at our institution were reviewed retrospectively. Histopathological measurement of DOI and TT was performed. The validation of DOI and TT as prognostic factors was conducted using a Kaplan–Meier survival analysis. TT had no association with disease-specific survival (DSS) or progression-free survival (PFS) in this cohort; however, increased DOI was significantly associated with decreased DSS but not correlated to decreased PFS. The T category of the 7th edition of AJCC was statistically associated with both DSS and PFS; however, the T category of the 8th edition of the AJCC was only associated with DSS. In this study group, TT could not be used as a prognostic factor, and DOI was not by itself sufficient to predict prognosis for early-stage OSCC. The T category in AJCC 8th Edition cannot be considered the sole prognostic factor for early OSCC, so additional prognostic factors may need to be considered. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)
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6 pages, 1243 KiB  
Case Report
Dilated Odontoma Arising in the Mandibular Third Molar Germ: Report of a Case of an Unusual Lesion in an Uncommon Site
by Francesca Zara, Giacomo D’Angeli, Alessandro Corsi, Antonella Polimeni and Gian Luca Sfasciotti
Diagnostics 2021, 11(12), 2256; https://doi.org/10.3390/diagnostics11122256 - 2 Dec 2021
Cited by 3 | Viewed by 2232
Abstract
Dilated odontoma is the most severe variant of dens invaginatus. It is extremely uncommon in the posterior mandible. It is thought to originate during the morpho-differentiation stage of dental development. However, its etiology and pathogenesis remain obscure. We report here the clinical and [...] Read more.
Dilated odontoma is the most severe variant of dens invaginatus. It is extremely uncommon in the posterior mandible. It is thought to originate during the morpho-differentiation stage of dental development. However, its etiology and pathogenesis remain obscure. We report here the clinical and pathologic findings of an incidentally discovered dilated odontoma arising in the left third mandibular molar germ of an 11-year-old male and a review of the pertinent literature. As dilated odontoma is not established as an independent entity in the current WHO classification of odontogenic tumors and is the result of a well-established developmental anomaly of the tooth (that is, the invagination of the enamel organ into the dental papilla), it should be better identified as dilated dens invaginatus. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)
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