Mass Transfer in Multiphase Reactors

A special issue of Fluids (ISSN 2311-5521).

Deadline for manuscript submissions: 30 November 2024 | Viewed by 681

Special Issue Editor


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Guest Editor
Institute of Chemical Engineering, Polish Academy of Sciences, 44-100 Gliwice, Poland
Interests: mass transfer; hydrodynamics; mixing; turbulence; nonlinear chaos theory; information entropy theory
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Special Issue Information

Dear Colleagues,

Mass transfer is the most important process in multiphase reactors. In many applications in the chemical industry, the mass transfer time determines the operational time of the multiphase reactors. The successful prediction of the volumetric liquid-phase mass transfer coefficients under various operating conditions is a challenging task. The effects of various parameters (including pressure and temperature) should be taken into account. The applicability of the classical mass transfer theories to newly proposed chemical reactors needs to be validated. A possible correction should be considered. The effects of turbulence and catalyst particles on the enhancement of mass transfer should be better characterized. Last but not least, the presence of a chemical reaction (especially a complex one) changes the mass transfer conditions and the bubble shape and behavior (in the case of bubbling) in the multiphase reactors and the process should be well modeled. Especially interesting are multiphase reactors operated with foaming systems (for instance aqueous alcohol solutions), electrolytes (salts), and surface active substances. Manuscripts dealing with these scientific problems are welcome in this new Special Issue.

Prof. Dr. Stoyan Nedeltchev
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • liquid-side mass transfer coefficient
  • classical mass transfer theories
  • correction factors
  • bubble shape effect
  • dilute alcohol solutions
  • electrolytes
  • surface active substances
  • local isotropic turbulence theory
  • new and classical multiphase reactors

Published Papers (1 paper)

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Research

13 pages, 4017 KiB  
Article
Characterization Data for the Establishment of Scale-Up and Process Transfer Strategies between Stainless Steel and Single-Use Bioreactors
by Vincent Bernemann, Jürgen Fitschen, Marco Leupold, Karl-Heinz Scheibenbogen, Marc Maly, Marko Hoffmann, Thomas Wucherpfennig and Michael Schlüter
Fluids 2024, 9(5), 115; https://doi.org/10.3390/fluids9050115 - 16 May 2024
Viewed by 370
Abstract
The reliable transfer of bioprocesses from single-use bioreactors (SUBs) of different scales to conventional stainless steel stirred-tank bioreactors is of steadily growing interest. In this publication, a scale-up study for SUBs with volumes of 200 L and 2000 L and the transfer to [...] Read more.
The reliable transfer of bioprocesses from single-use bioreactors (SUBs) of different scales to conventional stainless steel stirred-tank bioreactors is of steadily growing interest. In this publication, a scale-up study for SUBs with volumes of 200 L and 2000 L and the transfer to an industrial-scale conventional stainless steel stirred-tank bioreactor with a volume of 15,000 L is presented. The scale-up and transfer are based on a comparison of mixing times and the modeling of volumetric mass transfer coefficients kLa, measured in all three reactors in aqueous PBS/Kolliphor solution. The mass transfer coefficients are compared with the widely used correlation of van’t Riet at constant stirrer tip speeds. It can be shown that a van’t Riet correlation enables a robust and reliable prediction of mass transfer coefficients on each scale for a wide range of stirrer tip speeds and aeration rates. The process transfer from single-use bioreactors to conventional stainless steel stirred-tank bioreactors is proven to be uncritical concerning mass transfer performance. This provides higher flexibility with respect to bioreactor equipment considered for specific processes. Full article
(This article belongs to the Special Issue Mass Transfer in Multiphase Reactors)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

1. Comparison of the Performance of Single Use Bioreactors with Aerated Stirred Tank Bioreactors (200L up to 15000L)

Michael Schlüter

2. Gas-liquid Mass Transfer Intensification for Selective Alkyne Hydrogenation with an Advanced Elastic Catalytic Foam-bed Reactor

Maïté Michaud, Mohamad Fayad, Vincent Ritleng and David Edouard

3. Prediction of Mass Transfer Coefficients in Various Bubble Columns Entirely Based on Theoretical Concepts and Empirical Correlations

Stoyan Nedeltchev

4. Investigation of an Important Mass Transfer Ratio in Bubble Columns Operated with Various Organic Liquids in Both Homogeneous and Heterogeneous Regimes

Stoyan Nedeltchev 

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