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Data Science in Healthcare

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Digital Health".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 52995

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A printed edition of this Special Issue is available here.

Special Issue Editor

Hospital Services & Informatics, Philips Research, Eindhoven, The Netherlands
Interests: bioinformatics; oncology; data science; data management; machine learning; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Data science is an interdisciplinary field that applies numerous techniques, such as machine learning, neural networks, and deep learning, to create value, based on extracting knowledge and insights from available data. Advances in data science are having a major impact on healthcare. While advances in the sharing of medical information result in better and earlier diagnoses and more patient-tailored treatments, information management is also affected by trends such as increased patient-centricity (with shared decision making), self-care (e.g., using wearables), and integrated care delivery. The way in which health services are delivered is being revolutionized through the sharing and integration of health data across organizational boundaries. Via data science, researchers can deliver new approaches to merge, analyze, and process complex data and gain more actionable insights, understanding, and knowledge at individual and population level. This Special Issue focuses on how data science is used in healthcare (e.g., through predictive modeling) and on related topics such as data sharing and data management.

Dr. Tim Hulsen
Guest Editor

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Keywords

  • data science
  • big data
  • healthcare
  • medicine
  • prediction models
  • data sharing
  • data management

Published Papers (12 papers)

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Editorial

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4 pages, 264 KiB  
Editorial
Data Science in Healthcare: COVID-19 and Beyond
by Tim Hulsen
Int. J. Environ. Res. Public Health 2022, 19(6), 3499; https://doi.org/10.3390/ijerph19063499 - 16 Mar 2022
Cited by 2 | Viewed by 2278
Abstract
Data science is an interdisciplinary field that applies numerous techniques, such as machine learning (ML), neural networks (NN) and artificial intelligence (AI), to create value, based on extracting knowledge and insights from available ‘big’ data [...] Full article
(This article belongs to the Special Issue Data Science in Healthcare)

Research

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19 pages, 4486 KiB  
Article
Improved Machine Learning-Based Predictive Models for Breast Cancer Diagnosis
by Abdur Rasool, Chayut Bunterngchit, Luo Tiejian, Md. Ruhul Islam, Qiang Qu and Qingshan Jiang
Int. J. Environ. Res. Public Health 2022, 19(6), 3211; https://doi.org/10.3390/ijerph19063211 - 09 Mar 2022
Cited by 42 | Viewed by 7391
Abstract
Breast cancer death rates are higher than any other cancer in American women. Machine learning-based predictive models promise earlier detection techniques for breast cancer diagnosis. However, making an evaluation for models that efficiently diagnose cancer is still challenging. In this work, we proposed [...] Read more.
Breast cancer death rates are higher than any other cancer in American women. Machine learning-based predictive models promise earlier detection techniques for breast cancer diagnosis. However, making an evaluation for models that efficiently diagnose cancer is still challenging. In this work, we proposed data exploratory techniques (DET) and developed four different predictive models to improve breast cancer diagnostic accuracy. Prior to models, four-layered essential DET, e.g., feature distribution, correlation, elimination, and hyperparameter optimization, were deep-dived to identify the robust feature classification into malignant and benign classes. These proposed techniques and classifiers were implemented on the Wisconsin Diagnostic Breast Cancer (WDBC) and Breast Cancer Coimbra Dataset (BCCD) datasets. Standard performance metrics, including confusion matrices and K-fold cross-validation techniques, were applied to assess each classifier’s efficiency and training time. The models’ diagnostic capability improved with our DET, i.e., polynomial SVM gained 99.3%, LR with 98.06%, KNN acquired 97.35%, and EC achieved 97.61% accuracy with the WDBC dataset. We also compared our significant results with previous studies in terms of accuracy. The implementation procedure and findings can guide physicians to adopt an effective model for a practical understanding and prognosis of breast cancer tumors. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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18 pages, 1545 KiB  
Article
Validation of a Novel Predictive Algorithm for Kidney Failure in Patients Suffering from Chronic Kidney Disease: The Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD)
by Francesco Bellocchio, Caterina Lonati, Jasmine Ion Titapiccolo, Jennifer Nadal, Heike Meiselbach, Matthias Schmid, Barbara Baerthlein, Ulrich Tschulena, Markus Schneider, Ulla T. Schultheiss, Carlo Barbieri, Christoph Moore, Sonja Steppan, Kai-Uwe Eckardt, Stefano Stuard and Luca Neri
Int. J. Environ. Res. Public Health 2021, 18(23), 12649; https://doi.org/10.3390/ijerph182312649 - 30 Nov 2021
Cited by 9 | Viewed by 2418
Abstract
Current equation-based risk stratification algorithms for kidney failure (KF) may have limited applicability in real world settings, where missing information may impede their computation for a large share of patients, hampering one from taking full advantage of the wealth of information collected in [...] Read more.
Current equation-based risk stratification algorithms for kidney failure (KF) may have limited applicability in real world settings, where missing information may impede their computation for a large share of patients, hampering one from taking full advantage of the wealth of information collected in electronic health records. To overcome such limitations, we trained and validated the Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD), a novel algorithm predicting end-stage kidney disease (ESKD). PROGRES-CKD is a naïve Bayes classifier predicting ESKD onset within 6 and 24 months in adult, stage 3-to-5 CKD patients. PROGRES-CKD trained on 17,775 CKD patients treated in the Fresenius Medical Care (FMC) NephroCare network. The algorithm was validated in a second independent FMC cohort (n = 6760) and in the German Chronic Kidney Disease (GCKD) study cohort (n = 4058). We contrasted PROGRES-CKD accuracy against the performance of the Kidney Failure Risk Equation (KFRE). Discrimination accuracy in the validation cohorts was excellent for both short-term (stage 4–5 CKD, FMC: AUC = 0.90, 95%CI 0.88–0.91; GCKD: AUC = 0.91, 95% CI 0.86–0.97) and long-term (stage 3–5 CKD, FMC: AUC = 0.85, 95%CI 0.83–0.88; GCKD: AUC = 0.85, 95%CI 0.83–0.88) forecasting horizons. The performance of PROGRES-CKD was non-inferior to KFRE for the 24-month horizon and proved more accurate for the 6-month horizon forecast in both validation cohorts. In the real world setting captured in the FMC validation cohort, PROGRES-CKD was computable for all patients, whereas KFRE could be computed for complete cases only (i.e., 30% and 16% of the cohort in 6- and 24-month horizons). PROGRES-CKD accurately predicts KF onset among CKD patients. Contrary to equation-based scores, PROGRES-CKD extends to patients with incomplete data and allows explicit assessment of prediction robustness in case of missing values. PROGRES-CKD may efficiently assist physicians’ prognostic reasoning in real-life applications. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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12 pages, 1568 KiB  
Article
Development and Validation of a Machine Learning Model Predicting Arteriovenous Fistula Failure in a Large Network of Dialysis Clinics
by Ricardo Peralta, Mario Garbelli, Francesco Bellocchio, Pedro Ponce, Stefano Stuard, Maddalena Lodigiani, João Fazendeiro Matos, Raquel Ribeiro, Milind Nikam, Max Botler, Erik Schumacher, Diego Brancaccio and Luca Neri
Int. J. Environ. Res. Public Health 2021, 18(23), 12355; https://doi.org/10.3390/ijerph182312355 - 24 Nov 2021
Cited by 12 | Viewed by 3698
Abstract
Background: Vascular access surveillance of dialysis patients is a challenging task for clinicians. We derived and validated an arteriovenous fistula failure model (AVF-FM) based on machine learning. Methods: The AVF-FM is an XG-Boost algorithm aimed at predicting AVF failure within three months among [...] Read more.
Background: Vascular access surveillance of dialysis patients is a challenging task for clinicians. We derived and validated an arteriovenous fistula failure model (AVF-FM) based on machine learning. Methods: The AVF-FM is an XG-Boost algorithm aimed at predicting AVF failure within three months among in-centre dialysis patients. The model was trained in the derivation set (70% of initial cohort) by exploiting the information routinely collected in the Nephrocare European Clinical Database (EuCliD®). Model performance was tested by concordance statistic and calibration charts in the remaining 30% of records. Features importance was computed using the SHAP method. Results: We included 13,369 patients, overall. The Area Under the ROC Curve (AUC-ROC) of AVF-FM was 0.80 (95% CI 0.79–0.81). Model calibration showed excellent representation of observed failure risk. Variables associated with the greatest impact on risk estimates were previous history of AVF complications, followed by access recirculation and other functional parameters including metrics describing temporal pattern of dialysis dose, blood flow, dynamic venous and arterial pressures. Conclusions: The AVF-FM achieved good discrimination and calibration properties by combining routinely collected clinical and sensor data that require no additional effort by healthcare staff. Therefore, it can potentially enable risk-based personalization of AVF surveillance strategies. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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18 pages, 56909 KiB  
Article
Enhanced Sentinel Surveillance System for COVID-19 Outbreak Prediction in a Large European Dialysis Clinics Network
by Francesco Bellocchio, Paola Carioni, Caterina Lonati, Mario Garbelli, Francisco Martínez-Martínez, Stefano Stuard and Luca Neri
Int. J. Environ. Res. Public Health 2021, 18(18), 9739; https://doi.org/10.3390/ijerph18189739 - 16 Sep 2021
Cited by 7 | Viewed by 2412
Abstract
Accurate predictions of COVID-19 epidemic dynamics may enable timely organizational interventions in high-risk regions. We exploited the interconnection of the Fresenius Medical Care (FMC) European dialysis clinic network to develop a sentinel surveillance system for outbreak prediction. We developed an artificial intelligence-based model [...] Read more.
Accurate predictions of COVID-19 epidemic dynamics may enable timely organizational interventions in high-risk regions. We exploited the interconnection of the Fresenius Medical Care (FMC) European dialysis clinic network to develop a sentinel surveillance system for outbreak prediction. We developed an artificial intelligence-based model considering the information related to all clinics belonging to the European Nephrocare Network. The prediction tool provides risk scores of the occurrence of a COVID-19 outbreak in each dialysis center within a 2-week forecasting horizon. The model input variables include information related to the epidemic status and trends in clinical practice patterns of the target clinic, regional epidemic metrics, and the distance-weighted risk estimates of adjacent dialysis units. On the validation dates, there were 30 (5.09%), 39 (6.52%), and 218 (36.03%) clinics with two or more patients with COVID-19 infection during the 2-week prediction window. The performance of the model was suitable in all testing windows: AUC = 0.77, 0.80, and 0.81, respectively. The occurrence of new cases in a clinic propagates distance-weighted risk estimates to proximal dialysis units. Our machine learning sentinel surveillance system may allow for a prompt risk assessment and timely response to COVID-19 surges throughout networked European clinics. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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25 pages, 651 KiB  
Article
Optimized Neural Network Based on Genetic Algorithm to Construct Hand-Foot-and-Mouth Disease Prediction and Early-Warning Model
by Xialv Lin, Xiaofeng Wang, Yuhan Wang, Xuejie Du, Lizhu Jin, Ming Wan, Hui Ge and Xu Yang
Int. J. Environ. Res. Public Health 2021, 18(6), 2959; https://doi.org/10.3390/ijerph18062959 - 14 Mar 2021
Cited by 7 | Viewed by 2798
Abstract
Accompanied by the rapid economic and social development, there is a phenomenon of the crazy spread of many infectious diseases. It has brought the rapid growth of the number of people infected with hand-foot-and-mouth disease (HFMD), and children, especially infants and young children’s [...] Read more.
Accompanied by the rapid economic and social development, there is a phenomenon of the crazy spread of many infectious diseases. It has brought the rapid growth of the number of people infected with hand-foot-and-mouth disease (HFMD), and children, especially infants and young children’s health is at great risk. So it is very important to predict the number of HFMD infections and realize the regional early-warning of HFMD based on big data. However, in the current field of infectious diseases, the research on the prevalence of HFMD mainly predicts the number of future cases based on the number of historical cases in various places, and the influence of many related factors that affect the prevalence of HFMD is ignored. The current early-warning research of HFMD mainly uses direct case report, which uses statistical methods in time and space to have early-warnings of outbreaks separately. It leads to a high error rate and low confidence in the early-warning results. This paper uses machine learning methods to establish a HFMD epidemic prediction model and explore constructing a variety of early-warning models. By comparison of experimental results, we finally verify that the HFMD prediction algorithm proposed in this paper has higher accuracy. At the same time, the early-warning algorithm based on the comparison of threshold has good results. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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12 pages, 1419 KiB  
Article
Assessment of Thoracic Pain Using Machine Learning: A Case Study from Baja California, Mexico
by Veronica Rojas-Mendizabal, Cristián Castillo-Olea, Alexandra Gómez-Siono and Clemente Zuñiga
Int. J. Environ. Res. Public Health 2021, 18(4), 2155; https://doi.org/10.3390/ijerph18042155 - 23 Feb 2021
Cited by 2 | Viewed by 2505
Abstract
Thoracic pain is a shared symptom among gastrointestinal diseases, muscle pain, emotional disorders, and the most deadly: Cardiovascular diseases. Due to the limited space in the emergency department, it is important to identify when thoracic pain is of cardiac origin, since being a [...] Read more.
Thoracic pain is a shared symptom among gastrointestinal diseases, muscle pain, emotional disorders, and the most deadly: Cardiovascular diseases. Due to the limited space in the emergency department, it is important to identify when thoracic pain is of cardiac origin, since being a symptom of CVD (Cardiovascular Disease), the attention to the patient must be immediate to prevent irreversible injuries or even death. Artificial intelligence contributes to the early detection of pathologies, such as chest pain. In this study, the machine learning techniques were used, performing an analysis of 27 variables provided by a database with information from 258 geriatric patients with 60 years old average age from Medical Norte Hospital in Tijuana, Baja California, Mexico. The objective of this analysis is to determine which variables are correlated with thoracic pain of cardiac origin and use the results as secondary parameters to evaluate the thoracic pain in the emergency rooms, and determine if its origin comes from a CVD or not. For this, two machine learning techniques were used: Tree classification and cross-validation. As a result, the Logistic Regression model, using the characteristics proposed as second factors to consider as variables, obtained an average accuracy (μ) of 96.4% with a standard deviation (σ) of 2.4924, while for F1 a mean (μ) of 91.2% and a standard deviation (σ) of 6.5640. This analysis suggests that among the main factors related to cardiac thoracic pain are: Dyslipidemia, diabetes, chronic kidney failure, hypertension, smoking habits, and troponin levels at the time of admission, which is when the pain occurs. Considering dyslipidemia and diabetes as the main variables due to similar results with machine learning techniques and statistical methods, where 61.95% of the patients who suffer an Acute Myocardial Infarction (AMI) have diabetes, and the 71.73% have dyslipidemia. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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34 pages, 15667 KiB  
Article
COVID-19: Detecting Government Pandemic Measures and Public Concerns from Twitter Arabic Data Using Distributed Machine Learning
by Ebtesam Alomari, Iyad Katib, Aiiad Albeshri and Rashid Mehmood
Int. J. Environ. Res. Public Health 2021, 18(1), 282; https://doi.org/10.3390/ijerph18010282 - 01 Jan 2021
Cited by 52 | Viewed by 6674
Abstract
Today’s societies are connected to a level that has never been seen before. The COVID-19 pandemic has exposed the vulnerabilities of such an unprecedently connected world. As of 19 November 2020, over 56 million people have been infected with nearly 1.35 million deaths, [...] Read more.
Today’s societies are connected to a level that has never been seen before. The COVID-19 pandemic has exposed the vulnerabilities of such an unprecedently connected world. As of 19 November 2020, over 56 million people have been infected with nearly 1.35 million deaths, and the numbers are growing. The state-of-the-art social media analytics for COVID-19-related studies to understand the various phenomena happening in our environment are limited and require many more studies. This paper proposes a software tool comprising a collection of unsupervised Latent Dirichlet Allocation (LDA) machine learning and other methods for the analysis of Twitter data in Arabic with the aim to detect government pandemic measures and public concerns during the COVID-19 pandemic. The tool is described in detail, including its architecture, five software components, and algorithms. Using the tool, we collect a dataset comprising 14 million tweets from the Kingdom of Saudi Arabia (KSA) for the period 1 February 2020 to 1 June 2020. We detect 15 government pandemic measures and public concerns and six macro-concerns (economic sustainability, social sustainability, etc.), and formulate their information-structural, temporal, and spatio-temporal relationships. For example, we are able to detect the timewise progression of events from the public discussions on COVID-19 cases in mid-March to the first curfew on 22 March, financial loan incentives on 22 March, the increased quarantine discussions during March–April, the discussions on the reduced mobility levels from 24 March onwards, the blood donation shortfall late March onwards, the government’s 9 billion SAR (Saudi Riyal) salary incentives on 3 April, lifting the ban on five daily prayers in mosques on 26 May, and finally the return to normal government measures on 29 May 2020. These findings show the effectiveness of the Twitter media in detecting important events, government measures, public concerns, and other information in both time and space with no earlier knowledge about them. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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9 pages, 313 KiB  
Article
Association of Metabolically Healthy Obesity and Future Depression: Using National Health Insurance System Data in Korea from 2009–2017
by Yongseok Seo, Seungyeon Lee, Joung-Sook Ahn, Seongho Min, Min-Hyuk Kim, Jang-Young Kim, Dae Ryong Kang, Sangwon Hwang, Phor Vicheka and Jinhee Lee
Int. J. Environ. Res. Public Health 2021, 18(1), 63; https://doi.org/10.3390/ijerph18010063 - 23 Dec 2020
Cited by 7 | Viewed by 2172
Abstract
(1) Background: The health implications associated with the metabolically healthy obese (MHO) phenotype, in particular related to symptoms of depression, are still not clear. the purpose of this study is to check whether depression and metabolic status are relevant by classifying them into [...] Read more.
(1) Background: The health implications associated with the metabolically healthy obese (MHO) phenotype, in particular related to symptoms of depression, are still not clear. the purpose of this study is to check whether depression and metabolic status are relevant by classifying them into four groups in accordance with the MHO diagnostic standard. Other impressions seen were the differences between sexes and the effects of the MHO on the occurrence of depression. (2) Methods: A sample of 3,586,492 adult individuals from the National Health Insurance Database of Korea was classified into four categories by their metabolic status and body mass index: (1) metabolically healthy non-obese (MHN); (2) metabolically healthy obese (MHO); (3) metabolically unhealthy non-obese (MUN); and (4) metabolically unhealthy obese (MUO). Participants were followed for six to eight years for new incidences of depression. The statistical significance of the general characteristics of the four groups, as well as the mean differences in metabolic syndrome risk factors, was assessed with the use of a one-way analysis of variance (ANOVA). (3) Results: The MHN ratio in women was higher than in men (men 39.3%, women 55.2%). In both men and women, depression incidence was the highest among MUO participants (odds ratio (OR) = 1.01 in men; OR = 1.09 in women). It was concluded as well that, among the risk factors of metabolic syndrome, waist circumference was the most related to depression. Among the four groups, the MUO phenotype was the most related to depression. Furthermore, in women participants, MHO is also related to a higher risk of depressive symptoms. These findings indicate that MHO is not a totally benign condition in relation to depression in women. (4) Conclusion: Therefore, reducing metabolic syndrome and obesity patients in Korea will likely reduce the incidence of depression. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
11 pages, 779 KiB  
Article
Coronavirus Disease 2019 (COVID-19): A Modeling Study of Factors Driving Variation in Case Fatality Rate by Country
by Jennifer Pan, Joseph Marie St. Pierre, Trevor A. Pickering, Natalie L. Demirjian, Brandon K.K. Fields, Bhushan Desai and Ali Gholamrezanezhad
Int. J. Environ. Res. Public Health 2020, 17(21), 8189; https://doi.org/10.3390/ijerph17218189 - 05 Nov 2020
Cited by 17 | Viewed by 2617
Abstract
Background: The novel Severe Acute Respiratory Syndrome Coronavirus-2 has led to a global pandemic in which case fatality rate (CFR) has varied from country to country. This study aims to identify factors that may explain the variation in CFR across countries. Methods: We [...] Read more.
Background: The novel Severe Acute Respiratory Syndrome Coronavirus-2 has led to a global pandemic in which case fatality rate (CFR) has varied from country to country. This study aims to identify factors that may explain the variation in CFR across countries. Methods: We identified 24 potential risk factors affecting CFR. For all countries with over 5000 reported COVID-19 cases, we used country-specific datasets from the WHO, the OECD, and the United Nations to quantify each of these factors. We examined univariable relationships of each variable with CFR, as well as correlations among predictors and potential interaction terms. Our final multivariable negative binomial model included univariable predictors of significance and all significant interaction terms. Results: Across the 39 countries under consideration, our model shows COVID-19 case fatality rate was best predicted by time to implementation of social distancing measures, hospital beds per 1000 individuals, percent population over 70 years, CT scanners per 1 million individuals, and (in countries with high population density) smoking prevalence. Conclusion: Our model predicted an increased CFR for countries that waited over 14 days to implement social distancing interventions after the 100th reported case. Smoking prevalence and percentage population over the age of 70 years were also associated with higher CFR. Hospital beds per 1000 and CT scanners per million were identified as possible protective factors associated with decreased CFR. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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22 pages, 781 KiB  
Article
Digital Training for Non-Specialist Health Workers to Deliver a Brief Psychological Treatment for Depression in Primary Care in India: Findings from a Randomized Pilot Study
by Shital S. Muke, Deepak Tugnawat, Udita Joshi, Aditya Anand, Azaz Khan, Ritu Shrivastava, Abhishek Singh, Juliana L. Restivo, Anant Bhan, Vikram Patel and John A. Naslund
Int. J. Environ. Res. Public Health 2020, 17(17), 6368; https://doi.org/10.3390/ijerph17176368 - 01 Sep 2020
Cited by 30 | Viewed by 6041
Abstract
Introduction: Task sharing holds promise for scaling up depression care in countries such as India, yet requires training large numbers of non-specialist health workers. This pilot trial evaluated the feasibility and acceptability of a digital program for training non-specialist health workers to [...] Read more.
Introduction: Task sharing holds promise for scaling up depression care in countries such as India, yet requires training large numbers of non-specialist health workers. This pilot trial evaluated the feasibility and acceptability of a digital program for training non-specialist health workers to deliver a brief psychological treatment for depression. Methods: Participants were non-specialist health workers recruited from primary care facilities in Sehore, a rural district in Madhya Pradesh, India. A three-arm randomized controlled trial design was used, comparing digital training alone (DGT) to digital training with remote support (DGT+), and conventional face-to-face training. The primary outcome was the feasibility and acceptability of digital training programs. Preliminary effectiveness was explored as changes in competency outcomes, assessed using a self-reported measure covering the specific knowledge and skills required to deliver the brief psychological treatment for depression. Outcomes were collected at pre-training and post-training. Results: Of 42 non-specialist health workers randomized to the training programs, 36 including 10 (72%) in face-to-face, 12 (86%) in DGT, and 14 (100%) in DGT+ arms started the training. Among these participants, 27 (64%) completed the training, with 8 (57%) in face-to-face, 8 (57%) in DGT, and 11 (79%) in DGT+. The addition of remote telephone support appeared to improve completion rates for DGT+ participants. The competency outcome improved across all groups, with no significant between-group differences. However, face-to-face and DGT+ participants showed greater improvement compared to DGT alone. There were numerous technical challenges with the digital training program such as poor connectivity, smartphone app not loading, and difficulty navigating the course content—issues that were further emphasized in follow-up focus group discussions with participants. Feedback and recommendations collected from participants informed further modifications and refinements to the training programs in preparation for a forthcoming large-scale effectiveness trial. Conclusions: This study adds to mounting efforts aimed at leveraging digital technology to increase the availability of evidence-based mental health services in primary care settings in low-resource settings. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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Review

Jump to: Editorial, Research

12 pages, 621 KiB  
Review
Sharing Is Caring—Data Sharing Initiatives in Healthcare
by Tim Hulsen
Int. J. Environ. Res. Public Health 2020, 17(9), 3046; https://doi.org/10.3390/ijerph17093046 - 27 Apr 2020
Cited by 56 | Viewed by 9556
Abstract
In recent years, more and more health data are being generated. These data come not only from professional health systems, but also from wearable devices. All these ‘big data’ put together can be utilized to optimize treatments for each unique patient (‘precision medicine’). [...] Read more.
In recent years, more and more health data are being generated. These data come not only from professional health systems, but also from wearable devices. All these ‘big data’ put together can be utilized to optimize treatments for each unique patient (‘precision medicine’). For this to be possible, it is necessary that hospitals, academia and industry work together to bridge the ‘valley of death’ of translational medicine. However, hospitals and academia often are reluctant to share their data with other parties, even though the patient is actually the owner of his/her own health data. Academic hospitals usually invest a lot of time in setting up clinical trials and collecting data, and want to be the first ones to publish papers on this data. There are some publicly available datasets, but these are usually only shared after study (and publication) completion, which means a severe delay of months or even years before others can analyse the data. One solution is to incentivize the hospitals to share their data with (other) academic institutes and the industry. Here, we show an analysis of the current literature around data sharing, and we discuss five aspects of data sharing in the medical domain: publisher requirements, data ownership, growing support for data sharing, data sharing initiatives and how the use of federated data might be a solution. We also discuss some potential future developments around data sharing, such as medical crowdsourcing and data generalists. Full article
(This article belongs to the Special Issue Data Science in Healthcare)
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