Apoptosis and Autophagy as Strategies in Cancer Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 29 September 2024 | Viewed by 839
Special Issue Editor
Special Issue Information
Dear Colleagues,
Apoptosis and autophagy, two pathways involved in cell death, are extensive areas of research in the context of anticancer therapies. Both of these processes play a key role in maintaining homeostasis and participate in pathological processes related to carcinogenesis.
Apoptosis, a type of programmed cell death, is often suppressed in cancer cells and is considered a hallmark of cancer development.
Autophagy is a basic cellular mechanism occurring in every living cell, involving the digestion of cytoplasm fragments or entire cell organelles to obtain an endogenous energy source. It is associated with many intracellular signaling pathways, in particular nutrient-sensing mechanisms and cell-death-signaling cascades. The role of autophagy in cancer may be different; this process can not only activate and inhibit cell death but also facilitate switching between cell death mechanisms.
This Special Issue aims to present the latest original research and reviews on the modulation of the processes of apoptosis and autophagy in anticancer treatments. I hope that the latest research results presented in this Special Issue will contribute to a more profound understanding of the processes related to cell death and will be helpful in anticancer therapies.
Dr. Dorota Ciołczyk-Wierzbicka
Guest Editor
Manuscript Submission Information
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Keywords
- apoptosis
- autophagy
- cancer therapy/treatment
- drug resistance
- signaling pathways
