Molecular Pathology and Molecular Pharmacology of Chronic Pain

Dear Colleagues,

Chronic pain, a multifaceted and pervasive condition, presents a significant challenge to healthcare systems worldwide.

Its complex etiology and the diverse molecular mechanisms involved necessitate a comprehensive understanding to develop effective treatments. This Special Issue titled “Molecular Pathology and Molecular Pharmacology of Chronic Pain” aims to gather innovative research and reviews that shed light on the etiopathogenesis and molecular and therapeutic aspects of chronic pain management.

This Special Issue invites contributions from researchers and clinicians exploring the underlying causes and molecular pathways of chronic pain. We are particularly interested in articles that delve into the genetic, epigenetic, and environmental factors contributing to the onset and persistence of chronic pain. Additionally, we encourage submissions that examine novel molecular targets, biomarkers, and therapeutic strategies, including pharmacological and non-pharmacological approaches, to improve pain management.

We welcome original research articles, comprehensive reviews, and case studies that provide new insights into the molecular basis of chronic pain. Studies focusing on the interaction between molecular mechanisms and clinical manifestations, as well as the development of innovative diagnostic tools and treatment modalities, are highly encouraged.

Contributions to this Special Issue will not only enhance our understanding of chronic pain’s etiopathogenesis but also foster the development of more effective and personalized treatment strategies. This is an excellent opportunity for researchers and clinicians to share their findings with a global audience and contribute to a field of significant clinical and societal importance. We look forward to receiving your valuable contributions and advancing the discourse on chronic pain management through this Special Issue.

This Special Issue is supervised by Drs. Daniela Adamo, Giulia Ottaviani and Katia Rupel, and assisted by our Topical Advisory Panel Member: Dr. Canfora Federica (University of Naples Federico II).

Dr. Daniela Adamo
Dr. Giulia Ottaviani
Dr. Katia Rupel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• chronic pain
• etiopathogenesis
• molecular studies
• pain management
• therapeutic strategies
• biomarkers
• personalized medicine