ijms-logo

Journal Browser

Journal Browser

Molecular Perspective of Cardiovascular Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: closed (28 April 2024) | Viewed by 1175

Special Issue Editor


E-Mail Website
Guest Editor
Unit of Brain-Heart Axis: Cellular and Molecular Mechanisms, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy
Interests: cardiovascular disease; cardiology; thrombosis; thrombus formation, growth and resolution; coagulation; reactive oxygen species platelets; endothealial cells; pharmacology; signaling pathways
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Around one-third of total deaths are associated with cardiovascular diseases (CVDs); this presents a major challenge for modern-day healthcare. CVDs encompass several conditions that can affect the heart and blood vessels, including coronary artery diseases, carditis, heart failure, thromboembolism and so on. There are many risk factors for CVDs. More recently, a link was found between inflammation and atherosclerosis, and there have been some new perspectives on endothelial coagulation disorders, which all may lead to new breakthroughs in the clinical treatment of CVDs.

The aim of this Special Issue is to extend the knowledge of the underlying molecular mechanisms involved in CVDs. Both original research and review articles as well as short communications are strongly encouraged. Methodological studies focusing on new models and research techniques used to study these aspects are also welcome.

Dr. Silvia Barbieri
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular diseases
  • cardiology
  • inflammation
  • atherosclerosis
  • cardiomyopathy
  • endothelial cell

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

18 pages, 1473 KiB  
Review
Role of miRNA in Cardiovascular Diseases in Children—Systematic Review
by Marta Pasławska, Aleksandra Grodzka, Joanna Peczyńska, Beata Sawicka and Artur Tadeusz Bossowski
Int. J. Mol. Sci. 2024, 25(2), 956; https://doi.org/10.3390/ijms25020956 - 12 Jan 2024
Viewed by 913
Abstract
The number of children suffering from cardiovascular diseases (CVDs) is rising globally. Therefore, there is an urgent need to acquire a better understanding of the genetic factors and molecular mechanisms related to the pathogenesis of CVDs in order to develop new prevention and [...] Read more.
The number of children suffering from cardiovascular diseases (CVDs) is rising globally. Therefore, there is an urgent need to acquire a better understanding of the genetic factors and molecular mechanisms related to the pathogenesis of CVDs in order to develop new prevention and treatment strategies for the future. MicroRNAs (miRNAs) constitute a class of small non-coding RNA fragments that range from 17 to 25 nucleotides in length and play an essential role in regulating gene expression, controlling an abundance of biological aspects of cell life, such as proliferation, differentiation, and apoptosis, thus affecting immune response, stem cell growth, ageing and haematopoiesis. In recent years, the concept of miRNAs as diagnostic markers allowing discrimination between healthy individuals and those affected by CVDs entered the purview of academic debate. In this review, we aimed to systematise available information regarding miRNAs associated with arrhythmias, cardiomyopathies, myocarditis and congenital heart diseases in children. We focused on the targeted genes and metabolic pathways influenced by those particular miRNAs, and finally, tried to determine the future of miRNAs as novel biomarkers of CVD. Full article
(This article belongs to the Special Issue Molecular Perspective of Cardiovascular Diseases)
Show Figures

Figure 1

Back to TopTop