Molecular Research in Bacterial Vaginosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 5265
Special Issue Editor
2. Department of Clinical Laboratory Diagnostics, Saint Petersburg State Pediatric Medical University, Saint Petersburg 194100, Russia
Interests: medical microbiology; diagnosis of urogenital infections; molecular diagnostics; biofilms; bacterial vaginosis; infections in obstetrics and gynecology
Special Issue Information
Dear Colleagues,
Bacterial vaginosis (BV) is a common and often recurrent disease. It is a polymicrobial disease, but the main causative agent is Gardnerella vaginalis. Molecular studies have shown genetic heterogeneity and taxonomic diversity within the genus Gardnerella. At least 13 distinct groups were found, and they were classified as separate species within the taxon formerly known as G. vaginalis. These Gardnerella species are closely related genetically; only some of them (pathogenic) can be associated with BV, and non-pathogenic species are found in healthy women. Thanks to the methods of PCR, hybridization and sequencing, it has become possible to quantitatively detect and accurately identify bacteria, including those associated with BV.
Combining the efforts of the scientific community in the search for genetic markers of recurrent forms of BV using molecular research methods will allow us to understand the frequent recurrence of BV as well as determine the composition of biofilms formed by G. vaginalis and BV-associated microorganisms. In this Special Issue, we want to demonstrate the huge potential of research in the field of molecular studies of BV.
Prof. Dr. Alevtina M. Savicheva
Guest Editor
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Keywords
- bacterial vaginosis
- biofilms
- genital infections
- molecular diagnostics
- recurrent bacterial vaginosis
- molecular research
- Gardnerella vaginalis
- sequencing
- hybridization methods
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