Molecular Research on Thyroid and Thyroid Nodules

Dear Colleagues,

Thyroid nodules are common among Western populations, with an estimated prevalence of 50% among individuals aged above 60. However, only 5-10% of the nodules are cancerous, making identifying malignant lesions a substantial health concern for pathologists searching for novel and more accurate diagnostic tools and techniques. Integrating different sources of information, such as molecular and clinical data, has emerged as a transformative force in healthcare, improving medical practice in several aspects, including diagnosing tumors. Moreover, the correct choice of new and adequate statistical methods plays an essential role in this task, intending to (1) detect new diagnostic, prognostic, and predictive biomarkers easily translatable to the clinical practice, (2) detect new putative targets for innovative therapies in the precision medicine direction, and (3) understand the hidden patterns in the molecular modifications of thyroid disease. In this setting, we are inviting researchers working in the field to submit their research to this Special Issue, entitled "Molecular Research on Thyroid and Thyroid Nodules", which aims to provide a research platform to the original research articles and the latest reviews that cover all aspects of thyroid diseases.

Potential topics related to thyroid lesions include, but are not limited to, the following:

• Mass spectrometry;
• Transcriptomics;
• Proteomics;
• Metabolomics;
• Multi-omics integration;
• Biomarkers’ discovery;
• The characterization of cancer variants;
• Precision medicine.

Dr. Giulia Capitoli
Dr. Isabella Piga
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• thyroid lesion
• biomarkers’ discovery
• molecular information