Endometriosis and Endometriosis-Associated Cancer: Molecular Pathologies, Diagnosis and Therapeutic Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 1026
Special Issue Editors
Interests: endometriosis; gynecological surgery
Special Issue Information
Dear Colleagues,
The pathogenesis of endometriosis is not completely understood, but a growing body of evidence suggests that it is a multifactorial disease involving genetic, environmental, and immunological factors. Recent studies suggest the involvement of molecular mechanisms, including aberrant gene expression, the dysregulation of cell proliferation and apoptosis, altered immune response, and aberrant angiogenesis; however, the diagnostic and therapeutic implications of these possible mechanisms are not yet clear.
Previous studies have demonstrated an association between endometriosis and various types of cancers, including ovarian cancer, hematologic malignancies, breast cancer, and thyroid cancer. Although endometriosis is not malignant, it shares similar features with cancer, including the formation of local and distant lesions, the invasion of other tissues, and a resistance to apoptosis. Due to the non-specific symptoms, shared markers, and imaging resemblance of both conditions, it is difficult to diagnose endometriosis-associated cancers.
The Special Issue, entitled “Endometriosis and Endometriosis-Associated Cancer: Molecular Pathologies, Diagnosis and Therapeutic Strategies”, aims to provide a platform for the latest research and review articles covering molecular and biological studies of the factors associated with endometriosis in general and with endometriosis-associated cancers. A better understanding of the molecular mechanisms, as well as the diagnostic and therapeutic strategies, may ultimately improve the therapeutic outcomes of patients with endometriosis and its associated cancers.
Dr. Uri Dior
Dr. Tamar Perri
Guest Editors
Manuscript Submission Information
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Keywords
- endometriosis
- ovarian cancer
- breast cancer
- epigenetics
- gene expression
