Rheumatoid Arthritis: Pathogenesis and Treatments
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 940
Special Issue Editor
Interests: rheumatoid arthritis; pathophysiology; biological therapies; systemic connective tissue diseases; scleroderma; interstitial lung disease
Special Issue Information
Dear Colleagues,
Immune tolerance disorder causes the autoimmune disease RA. The exact pathogenesis of RA is not yet fully understood, but it is already known that the dominant factor is inappropriate activation of the immune system. A series of events ensues involving numerous cells of the immune system and cytokines that activate fibroblasts, chondrocytes and osteoclasts and influence the production of matrix metalloproteinases and other molecules causing tissue destruction.
Despite the changing knowledge and the creation of new molecules of biological and synthetic targeted drugs, there are many pathomechanisms that remain to be investigated in immunology.
This Special Issue is dedicated to all aspects of rheumatoid arthritis, modern therapies used in rheumatology and future possible drug combinations. When considering your submission, please keep in mind that IJMS is a journal of molecular science. However, submissions of clinical studies that include biomolecular experiments or pathological research with case sample data are welcome.
Dr. Katarzyna Romanowska-Próchnicka
Guest Editor
Manuscript Submission Information
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Keywords
- biological drugs
- targeted synthetic
- JAK inhibitors
- TNF-alpha inhibitors
- cytokine network
- immune response
- anti-drug antibodies
- drug resistance
- effectiveness
- side effects of drugs
- bioavailability
