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New Trends and Challenges in Polysaccharide Biomaterials

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 10 August 2024 | Viewed by 721

Special Issue Editors


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Guest Editor
Laboratory of Bioproducts Technology, Department of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 29, 50-370 Wrocław, Poland
Interests: plant polysaccharides; glycoconjugates; pectins; separation technology; chemical technology; chemical process design; process optimization; chromatography; carbohydrate chemistry; bioactivity; ethnomedicine; phytochemistry

E-Mail Website
Guest Editor
Laboratory of Bioproducts Technology, Department of Engineering and Technology of Chemical Processes, Organic and Pharmaceutical Technology Group, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 29, 50-370 Wroclaw, Poland
Interests: encapsulation; microencapsulation; controlled drug delivery; targeted drug delivery; biomaterials; polymers; polysaccharides; plant extracts; phytochemicals

Special Issue Information

Dear Colleagues,

Polysaccharide-based materials exhibit excellent natural biocompatibility and biodegradability, and they have received increased research attention due to their unique structural diversity. Due to their ability to form cross-linked multidimensional structures, they are widely used as components in pharmaceutical, biomedical, biotechnological products, and as materials for environmental purposes. The field of application of polysaccharides is very wide, ranging from their use in medicine, through food products, to cosmetics and biomedical usage, and still meets new targets. The presence of numerous hydroxyl and optionally carboxyl or amino groups along the polymer chains enables their chemical functionalization, thus extending their exploitation opportunities. Polysaccharides and their conjugates are used in the formation of micelles, micro- and nanoparticles, fibers, scaffolds, films, and hydrogels to meet various application needs. Therefore, such generations of biomaterials, in addition to their traditional uses, are widely studied for implementation in new applications, i.e., in broadly understood drug delivery and tissue engineering, as materials supporting wound healing, the immobilization of microorganisms, and even providing a favorable microenvironment for cell growth in tissue engineering.

This Special Issue aims to highlight the basic as well as applied aspects of advanced polysaccharide research in various research areas and present new trends and challenges related to the use of polysaccharide biomaterials, including, but not limited to, medicine, biochemistry, food chemistry, drug delivery, and environmental science, in the paper industry and biorefinery.

Dr. Izabela Pawlaczyk-Graja
Dr. Marta Tsirigotis-Maniecka
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polysaccharides
  • glucoconjugates
  • functional materials
  • hydrogels
  • nanoparticles and nanofibers
  • microparticles
  • cellulose derivatives
  • biocompatibility and biological functions
  • biomedical applications
  • tissue engineering
  • drug delivery
  • food chemistry

Published Papers (1 paper)

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Research

11 pages, 2058 KiB  
Article
Antioxidant Active Polysaccharides Extracted with Oxalate from Wild Blackthorn Fruits (Prunus spinosa L.)
by Peter Capek and Iveta Uhliariková
Int. J. Mol. Sci. 2024, 25(8), 4519; https://doi.org/10.3390/ijms25084519 - 20 Apr 2024
Viewed by 359
Abstract
Although several therapeutic effects have been attributed to wild blackthorn fruits, their use is still negligible. Purification of the antioxidant-active fraction, obtained from wild blackthorn fruits by hot ammonium oxalate extraction (Ao), yielded seven fractions after successive elution with water, sodium chloride and [...] Read more.
Although several therapeutic effects have been attributed to wild blackthorn fruits, their use is still negligible. Purification of the antioxidant-active fraction, obtained from wild blackthorn fruits by hot ammonium oxalate extraction (Ao), yielded seven fractions after successive elution with water, sodium chloride and sodium hydroxide solutions. The purified fractions differ in carbohydrates, proteins, and phenolics. About 60% of the applied Ao material was recovered from the column, with the highest yields eluted with 0.25 M NaCl solution, accounting for up to 70 wt% of all eluted material. Analyses have shown that two dominant fractions (3Fa and 3Fb) contain 72.8–81.1 wt% of galacturonic acids, indicating the prevalence of homogalacturonans (HG) with a low acetyl content and a high degree of esterification. The low content of rhamnose, arabinose and galactose residues in both fractions indicates the presence of RG-I associated with arabinogalactan. In terms of yield, the alkali-eluted fraction was also significant, as a dark brown-coloured material with a yield of ~15 wt% with the highest content of phenolic compounds of all fractions. However, it differs from other fractions in its powdery nature, which indicates a high content of salts that could not be removed by dialysis. Full article
(This article belongs to the Special Issue New Trends and Challenges in Polysaccharide Biomaterials)
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