Advances in Molecular Research of Diabetic Cardiomyopathy

Dear Colleagues,

This Special Issue will enclose a number of papers related to diabetic cardiomyopathy (DCM). DCM is the consequence of an altered glucose metabolism, leading to structural heart defects and altered activity. It is associated with oxidative stress, overactivation and expression of the renin angiotensin aldosterone system, abnormalities in intracellular calcium transport, mitochondrial dysfunction, and so on, but these mechanisms are not completely understood. To sum up, DCM is an independent complication of diabetes with a complex pathogenesis. There is no specific treatment so far, which mainly focuses on controlling blood sugar, lowering blood pressure and blood lipids, and improving lifestyles. Thus, this Special Issue will include research papers as well as reviews focusing on molecular studies highlighting the following:

• Mechanisms of DCM development.
• Therapeutic intervention, including possible clinical trials.
• Stem cell-based approaches for intervention strategies against DCM.
• Gene target therapy.

Dr. Giacomina Brunetti
Dr. Antonella Galeone
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• diabetic cardiomyopathy
• apoptosis
• diabetes
• myocardial fibrosis
• stem cells
• inflammation
• therapeutic approaches