Research Progress on 3D Cultures for Modeling the Microenvironment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 488
Special Issue Editor
Interests: cardiac microenvironment; cardiac repair mechanisms; 3D culture
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Methods and protocols for creating 3D cultures in vitro have been rapidly evolving in recent years, involving both biomaterials and structure design. Creating a 3D microenvironment for cell cultures allows complex interactions and stimuli that are functional for efficient phenotypic control and for mimicking tissue homeostasis and pathology. These tools can be used to successfully generate artificial tissues or cellular organoids that could be used for modeling the microenvironment in a physiologically relevant way, in addition to being used for drug screening or exploiting tissue engineering strategies in the clinical translation of regenerative medicine approaches.
This Special Issue will bring together scholars in the field of 3D cultures for the creation of in vitro microenvironments for the study of tissue homeostasis and pathology, particularly in the field of cardiovascular research. Potential topics include, but are not limited to, the following: novel methods for creating 3D cultures and tissue patches; study of the microenvironment in 3D cultures; modeling human diseases or pathological conditions in vitro; tissue engineering for regenerative medicine purposes; stem cell differentiation in 3D cultures; bioprinting of artificial tissues; development of smart biomaterials; and cell–extracellular matrix interactions in the context of 3D tissue development and function.
Dr. Isotta Chimenti
Guest Editor
Manuscript Submission Information
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Keywords
- 3D culture
- tissue engineering
- microenvironment
- disease modeling
- stem cell differentiation
- regenerative medicine
- biomaterials
- cell–extracellular matrix interaction
