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Clinical Practice Guidelines for the Treatment and Management of Peripartum Depression

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Mental Health".

Deadline for manuscript submissions: closed (30 July 2024) | Viewed by 5445

Special Issue Editor

Special Issue Information

Dear Colleagues,

We are pleased to announce a forthcoming Special Issue that seeks to deepen our understanding and enhance the treatment landscape for peripartum depression. As a prevalent yet underdiagnosed condition affecting up to 20% of women, peripartum depression demands our unwavering attention and commitment to improving its diagnosis and management. A recent consensus underscores the urgency of early detection and intervention, recognizing the potential long-term ramifications on both parental and child well-being. Screening tools such as the Edinburgh Postnatal Depression Scale (EPDS) have gained prominence and are endorsed by multiple guidelines. However, the complex features of this condition demands multifaceted approaches. First-line treatment, such as dynamically oriented psychotherapy or cognitive behavioral therapy (CBT), is recommended by various guidelines. Equally, antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), play a central role, necessitating careful consideration of the risks and benefits. Hormone therapy's role remains a subject of debate, prompting the need for further exploration. Holistic approaches encompass lifestyle changes, including exercise, sleep, and social support, as integral components of the treatment strategy. Alternative therapies, while promising, warrant rigorous investigation.

This Special Issue aims to synthesize cutting-edge research and practical insights in the field of peripartum depression. We welcome submissions that delve into various aspects, including:

  • Novel approaches for early detection and determining screening tools' effectiveness.
  • In-depth exploration of psychotherapeutic interventions and their implications.
  • Pharmacological treatments' efficacy, mechanisms, and potential adverse effects.
  • Navigating the complexities of medication during pregnancy and breastfeeding.
  • Role and implications of hormone therapy in peripartum depression.
  • Lifestyle interventions and their impact on symptom severity and recovery.
  • Alternative and complementary therapies' potential in peripartum depression management.
  • Real-world implementation and challenges in evidence-based treatment.
  • Long-term follow-up and outcomes for both mothers and children.

Dr. Silvia Cimino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • peripartum depression
  • early detection
  • evidence-based treatment
  • psychotherapy interventions
  • parental–infant well-being

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Related Special Issue

Published Papers (5 papers)

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Editorial

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4 pages, 194 KiB  
Editorial
Epidemiology, Etiology and Intervention Strategies for Peri-Partum Depression in Mothers
by Silvia Cimino
J. Clin. Med. 2023, 12(18), 5822; https://doi.org/10.3390/jcm12185822 - 7 Sep 2023
Viewed by 845
Abstract
The prevalence of peri-partum depression (PPD) varies widely across countries, with rates ranging from 10% to 15% depending on the screening method used and the country studied [...] Full article

Research

Jump to: Editorial

16 pages, 1052 KiB  
Article
A Network Analysis of Perinatal Depression, Anxiety, and Temperaments in Women in the First, Second, and Third Trimesters of Pregnancy
by Marianna Mazza, Caterina Brisi, Giorgio Veneziani, Francesco Maria Lisci, Ilenia Sessa, Marta Balocchi, Sara Rossi, Enrico Di Stasio, Giuseppe Marano, Francesca Abate, Maria Benedetta Anesini, Gianluca Boggio, Michele Ciliberto, Valeria De Masi, Cecilia Falsini, Ester Maria Marzo, Carla Avallone, Annamaria Serio, Angela Gonsalez del Castillo, Georgios Demetrios Kotzalidis, Daniela Pia Rosaria Chieffo, Antonio Lanzone, Giovanni Scambia, Carlo Lai and Gabriele Saniadd Show full author list remove Hide full author list
J. Clin. Med. 2024, 13(13), 3957; https://doi.org/10.3390/jcm13133957 - 5 Jul 2024
Cited by 1 | Viewed by 1026
Abstract
Background/Objectives: Although depression and anxiety are found to be affected by temperaments, little research has studied these relationships in pregnancy. The present study explored the associations among perinatal depression (PD), anxiety dimensions (state, trait, and generalized anxiety disorder (GAD)), and temperaments between women [...] Read more.
Background/Objectives: Although depression and anxiety are found to be affected by temperaments, little research has studied these relationships in pregnancy. The present study explored the associations among perinatal depression (PD), anxiety dimensions (state, trait, and generalized anxiety disorder (GAD)), and temperaments between women in the three trimesters of pregnancy through a network analysis approach. Moreover, differences in the severity of PD and anxiety between women in the three trimesters were evaluated. Methods: Women in first (N = 31), second (N = 184), and third (N = 54) trimesters of pregnancy were recruited in the present cross-sectional study. The network analysis included PD, anxiety dimensions, and temperaments. Three network models were estimated, and ANOVAs evaluated the differences in the severity of PD and anxiety, including trimesters as a between-subject factor. Results: PD and GAD were the nodes most strongly connected across the three groups. Cyclothymic, depressive, and anxious temperaments were most frequently associated with PD and GAD. Hyperthymic temperament was in the periphery of the three networks. Lastly, women in the first trimester had the highest severity of PD and GAD. Conclusions: PD and GAD showed the strongest associations. Anxiety dimensions had positive associations with PD and GAD, suggesting their role as possible risk factors. Temperaments were differently associated within the network between the three groups. Clinical interventions during pregnancy should target the central variables, considering their direct and indirect relationships. Full article
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9 pages, 667 KiB  
Article
The Relationship between Body Mass Index, Body Dissatisfaction and Mood Symptoms in Pregnant Women
by Caterina Grano, Mariacarolina Vacca and Caterina Lombardo
J. Clin. Med. 2024, 13(8), 2424; https://doi.org/10.3390/jcm13082424 - 21 Apr 2024
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Abstract
Background: High body mass and adiposity during pregnancy can contribute to psychological distress, and body dissatisfaction may be a potential underlying mechanism of this association. Objective. This study aimed to evaluate the mediational role of body dissatisfaction in the relationship between body [...] Read more.
Background: High body mass and adiposity during pregnancy can contribute to psychological distress, and body dissatisfaction may be a potential underlying mechanism of this association. Objective. This study aimed to evaluate the mediational role of body dissatisfaction in the relationship between body mass index (BMI) and depressive and anxious symptoms, respectively. Methods: Given the cross-sectional design of this study, two alternative models were investigated, positing that BMI was related to depressive (Model 1a) and anxious symptoms (Model 2a), which, in turn, predicted body dissatisfaction. Seventy-two pregnant women in the third trimester of pregnancy completed the Body Image Disturbance Questionnaire, the Beck Depression Inventory-II and the State-Trait Anxiety Inventory, as well as a demographic form assessing their BMI. Results: As hypothesized, body dissatisfaction mediated the relationship between BMI and psychopathological symptoms. Moreover, the alternative models of reverse mediation were also significant, suggesting that psychopathological symptoms mediated the relationship between BMI and body dissatisfaction. Findings from both the hypothesized and alternative models suggested that, on the one hand, higher distress symptoms associated with body dissatisfaction would result from high BMI and, on the other hand, that body dissatisfaction may result from the effect of BMI on distress symptoms. Conclusions: The present study suggests that body image theory and practice should be implemented by the inclusion of evidence-based clinical interventions for promoting psychological well-being during the antenatal period. Full article
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9 pages, 224 KiB  
Article
Peripartum Depressive Symptoms in Fathers during the COVID-19 Pandemic
by Silvia Cimino and Luca Cerniglia
J. Clin. Med. 2024, 13(6), 1772; https://doi.org/10.3390/jcm13061772 - 20 Mar 2024
Viewed by 832
Abstract
Background: This research investigates peripartum depression in fathers during COVID-19, focusing on how pandemic-related distress is associated with paternal depressive symptoms and the quality of father–child feeding interactions. The primary objective was to understand if the pandemic has influenced depressive symptoms in [...] Read more.
Background: This research investigates peripartum depression in fathers during COVID-19, focusing on how pandemic-related distress is associated with paternal depressive symptoms and the quality of father–child feeding interactions. The primary objective was to understand if the pandemic has influenced depressive symptoms in new fathers and how these symptoms impact their interactions with their children, especially during feeding. Methods: Utilizing a cross-sectional design, the research employs online surveys and remote observation to gather data from 243 Italian fathers. The analysis involves established psychometric tools like the Symptoms Check-List/90R and the Peritraumatic Distress Index to assess the severity of depressive symptoms and their correlation with father–child interaction exchanges, observed through the SVIA. Results: The fathers’ peritraumatic distress due to COVID-19 was significantly and positively associated with the level of their depressive symptoms and negatively correlated with the quality of their feeding interactions with their children. Moreover, elevated levels of peritraumatic stress were notably predictive of higher instances of depressive symptoms in the fathers. Further, higher levels of stress associated with COVID-19 were predictive of a poorer quality of father–child interactions. Conclusions: This research highlights the need for inclusive perinatal support programs, offering foundational insights into paternal mental health during pandemics. Full article
23 pages, 826 KiB  
Article
Impact of Pregnancy on Self-Efficacy and Personal Competence in the Context of Risk of Depression, Mental Health Status, and Satisfaction with Life
by Agnieszka Kułak-Bejda, Ilknur Avci Aydin, Dilek Çelik Eren, Lambrini Kourkouta, Areti Tsaloglidou, Konstantinos Koukourikos, Andriej Szpakow, Natallia Khvoryk, Liudmila Hutsikava and Napoleon Waszkiewicz
J. Clin. Med. 2024, 13(2), 533; https://doi.org/10.3390/jcm13020533 - 17 Jan 2024
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Abstract
For many women, pregnancy and childbirth are often accompanied by strong emotions related to fear, stress, and anxiety about the health of the woman and her child. This study aimed to assess the effect of pregnancy on the risk of depression, mental health [...] Read more.
For many women, pregnancy and childbirth are often accompanied by strong emotions related to fear, stress, and anxiety about the health of the woman and her child. This study aimed to assess the effect of pregnancy on the risk of depression, mental health status, and satisfaction with life in women in Poland, Greece, Turkey, Belarus, and Russia. Material and methods: A cross-sectional comparative study was conducted among 2017 women surveyed, including 584 pregnant women, 528 postpartum women, and 906 women who had never been pregnant (the comparative group) from Poland, Greece, Turkey, Belarus, and Russia. The sample selection was purposive. Surveys were collected between November 2021 and December 2022. The study used the Beck Depression Inventory (BDI) Scale, the Satisfaction with Life Scale (SWLS), the Edinburgh Postpartum Depression Scale (EPDS), the GHQ-28 (General Health Questionnaire), the Schwarzer Generalized Self-Efficacy Scale (GSES), and the KompOs Personal Competence Scale. Results: A significantly lower risk of depression was observed in postpartum women in Poland and amongst pregnant women in Turkey. Pregnant women in Turkey (28.9 points) presented the highest satisfaction with life, while the lowest satisfaction was found amongst pregnant women in Poland and Greece (25.2 and 25.1 points, respectively). In Poland and Belarus, a higher risk of depression was noticed in women who had undergone an artificial abortion. In Turkey, a positive correlation was found in pregnant women concerning the number of children they had with a measure of depression and a negative correlation with life satisfaction. In Greece, non-pregnant women showed no correlation between mental status and scores on the GSES. Scores on satisfaction with SWLS were positively correlated with a sense of power, and the strength of the correlation was similar to results on the BDI and GHQ measures. Postpartum depression, according to the EPDS, was also the most severe in Turkish women. Conclusions: The highest risk of depression was shown in the control group and amongst pregnant and postpartum women in Turkey and Greece, and the lowest such risk was in Poland. Pregnant and postpartum women showed by far the highest satisfaction with life in Turkey and the lowest in women from Greece. The risk of depression, the level of satisfaction with life, and the mental health of pregnant women were not influenced by the type of last delivery. However, the duration of the last delivery influenced the group from Belarus, and having children affected the mental health of women in the group from Turkey. Full article
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