Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 11124
Special Issue Editors
Interests: immunodermatology; autoimmune skin disorders; connective tissue diseases; autoimmune blistering diseases; diagnostic tools in dermatology
Interests: immunodermatology; autoimmune connective tissue diseases; non-invasive diagnostics of skin diseases
Interests: itch; psychodermatology; psoriasis; autoimmune connective tissue disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Connective tissue diseases (CTDs) encompass a diverse group of autoimmune diseases, including systemic lupus erythematosus (SLE), scleroderma, dermatomyositis and rarer overlap syndromes. Despite different clinical symptoms, these entities share common pathogenetic mechanisms rooted in abnormal immune responses. Each connective tissue disease manifests itself in a wide spectrum of symptoms, from the mild involvement of one system to severe complications affecting multiple organs.
The clinical presentation of CTD is very diverse, making the diagnosis of this disease challenging. Initial symptoms often include fatigue, joint pain and skin lesions. Diagnosis is based on a combination of clinical criteria, laboratory tests and imaging studies. Treatment strategies aim to manage symptoms and modify the underlying immune dysregulation. The basis of therapy comprises immunosuppressive drugs, corticosteroids and disease-modifying drugs. Moreover, early intervention and a personalized approach are key to optimizing the outcomes.
This comprehensive understanding of the common pathogenesis and distinct clinical profiles of CTD highlights the need for tailored diagnostic and therapeutic strategies. Ongoing research is aimed at understanding the complexity of these diseases, constantly searching for new therapeutic options and improving comprehensive patient care.
The objective of this Special Issue is to offer a comprehensive perspective on the present and evolving understanding of the clinical characteristics and prolonged consequences associated with connective tissue diseases. This encompasses an exploration of disease phenotypes, therapeutic approaches and biomarkers, aiming to provide an in-depth overview of the diverse aspects within the realm of connective tissue diseases.
Prof. Dr. Agnieszka Żebrowska
Prof. Dr. Aleksandra Dańczak-Pazdrowska
Prof. Dr. Adam Reich
Guest Editors
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Keywords
- connective tissue diseases
- lupus erythematosus
- scleroderma
- dermatomyositis
- MCTD
- clinical picture
- spectrum of clinical symptoms
- treatment
- complications
- clinical follow-up
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