Molecular Insights and Treatment of Diabetic Retinopathy

Dear Colleagues,

The worldwide increase in the diabetic population predicts a significant rise in the number of individuals with diabetes-related retinal diseases. An overwhelming cause of vision loss in diabetic retinopathy is related to excess vascular permeability, the development of macular edema, and uncontrolled neovascularization. Despite the use of laser photocoagulation, and available therapeutics, the majority of patients do not fully recover from vision loss. Although anti-VEGF approaches work well they are not always successful in DR patients. Therefore, identifying alternative or supplemental therapeutic approaches for DR treatment is acutely needed.  Research into areas involving vascular structural alterations and blood retinal barrier characteristics has uncovered significant underlying factors that participate in these pathogenetic changes. This Special Issue will highlight current insights underlying molecular mechanisms and novel approaches towards better understanding and treatment of DR.

Prof. Dr. Sayon Roy
Guest Editor

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