Dear Colleagues,

Research shows that dementia and Alzheimer's are leading causes of the need for residential care in older adults. Estimates indicate that approximately 46 million people worldwide suffer from these conditions.

Medical evidence shows that both pharmacological and integrated non-pharmacological treatment, such as physical and cognitive rehabilitation, can improve the symptomatology of these patients, with a favorable impact on their quality of life.

For a forthcoming Special Issue of the Journal of Clinical Medicine (indexed in PubMed), we invite researchers to contribute original research articles (priority will be given to experimental studies) as well as review articles that stimulate continued efforts to better understand the relationship between rehabilitation and Alzheimer's disease and dementia.

Potential issues may include, but are not limited to:

• The effects of exercise on Alzheimer's disease and dementia;
• The effects of physical and cognitive rehabilitation on Alzheimer's disease and dementia;
• New non-pharmacological therapies in the management of symptoms of Alzheimer's disease and dementia;
• Multidisciplinary approaches to Alzheimer’s disease and dementia;
• Cellular, molecular and psychological mechanisms that may influence the Alzheimer's disease and dementia process.

Dr. Juan Rodríguez-Mansilla
Dr. Cristoforo Comi
Dr. María Jiménez-Palomares
Dr. Blanca Gonzalez-Sanchez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cognition
• dementia
• rehabilitation
• exercise
• memory
• physical activity
• Alzheimer’s disease
• non-pharmacological therapies