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Kidney Diseases and Kidney Involvement in Pregnancy: The Crossroad of...
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Kidney Diseases and Kidney Involvement in Pregnancy: The Crossroad of Obstetrics, Nephrology, Urology and Internal Medicine – Part II

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 5206

Special Issue Editors

Prof. Dr. Giorgina Barbara Piccoli

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Guest Editor
1. Nephrology, Centre Hospitalier Le Mans, 72037 Le Mans, France
2. Department of Clinical and Biological Sciences, ASOU San Luigi, University of Turin, 10124 Turin, Italy
Interests: CKD; dietary management and CKD; hemodialysis; tailored dialysis (daily dialysis, incremental dialysis); ethical aspects; long term outcomes; pregnancy and CKD; pregnancy and dietary management in kidney transplantation
Special Issues, Collections and Topics in MDPI journals
Dr. Rossella Attini

E-Mail Website
Guest Editor
Department of Surgery, University of Torino, 10126 Torino, Italy
Interests: obstetrics; pathological pregnancy; kidney disease in pregnancy; urological disease in pregnancy; cardiotocography; fetal monitoring in labour; STAN; operative delivery
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Gianfranca Cabiddu

E-Mail Website
Guest Editor
1. Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy
2. Nephrology, Transplantation and Dialysis, San Michele Hospital, ARNAS G. Brotzu, Cagliari, Italy
Interests: clinical nephrology (in particular: pregnancy and kidney diseases; lupus and immunologic renal diseases; nutritional treatment of chronic kidney diseases and predialysis care; rare diseases); dialysis (and in particular peritoneal dialysis); epidemiology of chronic kidney disease and of its treatments
Dr. Massimo Torreggiani

E-Mail Website
Guest Editor
Néphrologie Et Dialyse, Centre Hospitalier Le Mans, 194 Avenue Rubillard, 72000 Le Mans, France
Interests: chronic kidney disease; nutrition in CKD; diabetic nephropathy; aging; dialysis; pregnancy and CKD
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Obstetric Nephrology is a branch of clinical nephrology that has gained increasing attention in recent years. This is why we have decided to update our previous Special Issue ("Kidney Diseases and Kidney Involvement in Pregnancy: the Crossroad of Obstetrics, Nephrology, Urology and Internal Medicine") dedicated to kidney diseases and pregnancy, with the hope that it will be able to give further voice to this issue that is not only clinically relevant, but also a basic determinant of quality of life and of the fulfilment of the goal of living with CKD and having a “normal”, fruitful life.

In 2018, World Kidney Day coincided with International Woman’s Day, and so the yearly campaign focused on women and kidney diseases in general, as well as on pregnancy and kidney diseases in particular. Since then, and our previous Special Issue published in the same year, the notion that even mild renal involvement is relevant for the development of pregnancy complications has been further stressed, and this has led to the expansion of the concept of “high risk pregnancy”.

Meanwhile, the association between preeclampsia, HELLP syndrome and intrauterine growth restriction and future risk of chronic kidney disease and hypertension in the mother, as well as increased risk of cardiovascular, metabolic and kidney diseases in the offspring has been further disentangled, and the first programs aimed at improving multidisciplinary care are being established.

New evidence on dialysis is accumulating, suggesting that kidney disease during pregnancy may be more frequent than previously thought. There is need for studies on assisted fertilisation techniques and all stages of CKD.

While knowledge has certainly progressed over these last four years, there is still need for further studies, due to the extreme heterogeneity of kidney diseases in terms of pathogenesis, causes, stages and associated conditions, in order to improve the health of CKD-suffering mothers and their babies.

Besides maternal aspects, this Special Issue also welcomes papers on fatherhood in CKD.

With the hope that this Special Issue will be a special occasion for sharing knowledge, please contact us in case you need financial support, as we aim to find targeted solutions allowing authors from emerging countries or with limited budgets to share their valuable experiences.

Prof. Dr. Giorgina Barbara Piccoli
Dr. Rossella Attini
Prof. Dr. Gianfranca Cabiddu
Dr. Massimo Torreggiani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic kidney disease
  • pregnancy
  • dialysis
  • preeclampsia
  • HELLP
  • small for gestational age
  • intrauterine growth restriction
  • hypertensive disorders of pregnancy
  • hypertension
  • neonatal care
  • quality of life

Published Papers (3 papers)

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Editorial

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5 pages, 3805 KiB  
Editorial
Pregnancy and Kidney Diseases: Multidisciplinary Follow-Up and the Vicious Circles Involving Pregnancy and CKD, Preeclampsia, Preterm Delivery and the Kidneys
by Giorgina Barbara Piccoli, Rossella Attini, Massimo Torreggiani and Gianfranca Cabiddu
J. Clin. Med. 2022, 11(9), 2535; https://doi.org/10.3390/jcm11092535 - 30 Apr 2022
Cited by 3 | Viewed by 1548
Abstract
Thomas Addis, the father of nephrology, once wrote that a clinician is complex, “he is part craftsman, part practical scientist, and part historian” [...] Full article
(This article belongs to the Special Issue Kidney Diseases and Kidney Involvement in Pregnancy: The Crossroad of Obstetrics, Nephrology, Urology and Internal Medicine – Part II)
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Review

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9 pages, 267 KiB  
Review
Kidney Biopsy in Pregnant Women with Glomerular Diseases: Focus on Lupus Nephritis
by Gabriella Moroni, Marta Calatroni, Beatriz Donato and Claudio Ponticelli
J. Clin. Med. 2023, 12(5), 1834; https://doi.org/10.3390/jcm12051834 - 24 Feb 2023
Cited by 1 | Viewed by 1598
Abstract
Despite significant improvements of renal and obstetrical management, pregnancies in women with glomerular diseases and with lupus nephritis continue to be associated with increased complications both for the mother and the fetus as compared to those of pregnancies in healthy women. To reduce [...] Read more.
Despite significant improvements of renal and obstetrical management, pregnancies in women with glomerular diseases and with lupus nephritis continue to be associated with increased complications both for the mother and the fetus as compared to those of pregnancies in healthy women. To reduce the risk of these complications, planning pregnancy in a phase of stable remission of the underlining disease is necessary. A kidney biopsy is an important event in any phase of pregnancy. A kidney biopsy can be of help during counselling before pregnancy in cases of incomplete remission of the renal manifestations. In these situations, histological data may differentiate active lesions that require the reinforcement of therapy from chronic irreversible lesions that may increase the risk of complications. In pregnant women, a kidney biopsy can identify new-onset systemic lupus erythematous (SLE) and necrotizing or primitive glomerular diseases and distinguish them from other, more common complications. Increasing proteinuria, hypertension, and the deterioration of kidney function during pregnancy may be either due to a reactivation of the underlying disease or to pre-eclampsia. The results of the kidney biopsy suggest the need to initiate an appropriate treatment, allowing the progression of the pregnancy and the fetal viability or the anticipation of delivery. Data from the literature suggest avoiding a kidney biopsy beyond 28 weeks of gestation to minimize the risks associated with the procedure vs. the risk of preterm delivery. In case of the persistence of renal manifestations after delivery in women with a diagnosis of pre-eclampsia, a renal kidney assessment allows the final diagnosis and guides the therapy. Full article
(This article belongs to the Special Issue Kidney Diseases and Kidney Involvement in Pregnancy: The Crossroad of Obstetrics, Nephrology, Urology and Internal Medicine – Part II)
20 pages, 1342 KiB  
Review
The Hypertensive Disorders of Pregnancy: A Focus on Definitions for Clinical Nephrologists
by Elisa Longhitano, Rossella Siligato, Massimo Torreggiani, Rossella Attini, Bianca Masturzo, Viola Casula, Ida Matarazzo, Gianfranca Cabiddu, Domenico Santoro, Elisabetta Versino and Giorgina Barbara Piccoli
J. Clin. Med. 2022, 11(12), 3420; https://doi.org/10.3390/jcm11123420 - 14 Jun 2022
Cited by 4 | Viewed by 3406
Abstract
About 5–10% of pregnancies are complicated by one of the hypertensive disorders of pregnancy. The women who experience these disorders have a greater risk of having or developing kidney diseases than women with normotensive pregnancies. While international guidelines do not provide clear indications [...] Read more.
About 5–10% of pregnancies are complicated by one of the hypertensive disorders of pregnancy. The women who experience these disorders have a greater risk of having or developing kidney diseases than women with normotensive pregnancies. While international guidelines do not provide clear indications for a nephrology work-up after pregnancy, this is increasingly being advised by nephrology societies. The definitions of the hypertensive disorders of pregnancy have changed greatly in recent years. The objective of this short review is to gather and comment upon the main definitions of the hypertensive disorders of pregnancy as a support for nephrologists, who are increasingly involved in the short- and long-term management of women with these disorders. Full article
(This article belongs to the Special Issue Kidney Diseases and Kidney Involvement in Pregnancy: The Crossroad of Obstetrics, Nephrology, Urology and Internal Medicine – Part II)
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