Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.7
2.7
Journals
JDB
Special Issues
Conserved and Divergent Mechanisms Regulating Muscle Development and Regeneration
share announcement

Conserved and Divergent Mechanisms Regulating Muscle Development and Regeneration

A special issue of Journal of Developmental Biology (ISSN 2221-3759).

Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 12481

Special Issue Editor

Prof. Dr. Frederic Relaix

E-Mail Website
Guest Editor
Université Paris Est Créteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Mondor Institute for Biomedical Research (IMRB), F-94010 Créteil, France; EnvA, IMRB, F-94700 Maisons-Alfort, France
Interests: muscle stem cells in the forefront of myogenesis; interactions of stem cells with their environment; pathogenesis and therapy of neuromuscular disorders; preclinical modeling

Special Issue Information

Dear Colleagues,

Skeletal muscle shows robust regenerative capacity and is able to undergo several rounds of regeneration in response to multiple injuries. This capacity depends on satellite cells, the stem cells of the adult muscle. During regeneration, satellite cells proliferate and differentiate to form new muscle tissue, but they also self-renew to maintain the satellite cell pool. Muscle Stem cells originate from a pool of embryonic/fetal progenitors. Satellite cells and muscle progenitor cells share features like Pax7 expression, the ability to self-renew or to differentiate, and are thought to rely on similar molecular mechanisms for differentiation. Thus, the analysis of developmental processes can guide satellite cell research. Yet, differences in molecular mechanisms have also become apparent. This Special Issue of the Journal of Developmental Biology will provide an overview of the current understanding of skeletal muscle stem development and regeneration, focusing on conserved and divergent mechanisms Contributions can be reviews, as well as research papers, covering comparative analysis of development and regeneration of skeletal muscle.

Prof. Dr. Frederic Relaix
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skeletal muscle
  • muscle stem cells
  • development
  • regeneration
  • myogenesis

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

14 pages, 931 KiB  
Review
Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
by Matthew J Borok, Despoina Mademtzoglou and Frederic Relaix
J. Dev. Biol. 2020, 8(1), 4; https://doi.org/10.3390/jdb8010004 - 11 Feb 2020
Cited by 15 | Viewed by 4934
Abstract
The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have [...] Read more.
The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have a number of functions in skeletal muscle, from embryonic to postnatal development. Furthermore, complementary studies have recently demonstrated that specific components of the pathway are required for efficient muscle regeneration. Full article
(This article belongs to the Special Issue Conserved and Divergent Mechanisms Regulating Muscle Development and Regeneration)
►▼ Show Figures

Figure 1

21 pages, 3584 KiB  
Review
The Developmental Phases of Zebrafish Myogenesis
by Samuel R. Keenan and Peter D. Currie
J. Dev. Biol. 2019, 7(2), 12; https://doi.org/10.3390/jdb7020012 - 2 Jun 2019
Cited by 31 | Viewed by 7128
Abstract
The development and growth of vertebrate axial muscle have been studied for decades at both the descriptive and molecular level. The zebrafish has provided an attractive model system for investigating both muscle patterning and growth due to its simple axial musculature with spatially [...] Read more.
The development and growth of vertebrate axial muscle have been studied for decades at both the descriptive and molecular level. The zebrafish has provided an attractive model system for investigating both muscle patterning and growth due to its simple axial musculature with spatially separated fibre types, which contrasts to complex muscle groups often deployed in amniotes. In recent years, new findings have reshaped previous concepts that define how final teleost muscle form is established and maintained. Here, we summarise recent findings in zebrafish embryonic myogenesis with a focus on fibre type specification, followed by an examination of the molecular mechanisms that control muscle growth with emphasis on the role of the dermomyotome-like external cell layer. We also consider these data sets in a comparative context to gain insight into the evolution of axial myogenic patterning systems within the vertebrate lineage. Full article
(This article belongs to the Special Issue Conserved and Divergent Mechanisms Regulating Muscle Development and Regeneration)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop