Molecular Mechanisms of Cancer Progression and Recurrence

Dear Colleagues,

Cancer is a multifaceted disease that involves not just appearance at a single body site, but rather has the potential of spreading throughout body organs through the metastasis process. In addition to that, it poses a number of problems in its treatment, and recurrence is a harsh reality for this disease. Factors within the tumor microenvironment play key roles in the process of recurrence and metastasis. These factors include stroma cells and extracellular matrices. Deregulated processes, due to factors such as genetic mutations, including angiogenesis, tumor suppression, repair mechanisms and cell cycle, contribute to the so-called cancer phenotype.

The aim of this Special Issue is to provide a collection of research articles, research letters and reviews that deal with the molecular mechanisms of cancer progression and recurrence. The submitted papers may cover any aspect of cancer biology that deals with these issues (not leaving out the interplay with the immune system). Papers that refer to clinical processes based on targeting any cancer progression and recurrence mechanism will be considered too.

Dr. Nikos G. Gavalas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cancer
• metastasis
• angiogenesis
• recurrence
• clinical
• molecular
• mechanisms
• mutations