Dear Colleagues,

Polyphenols are components of many plants, being mostly distributed in fruits, vegetables and cereals. These compounds possess anti-inflammatory and anti-oxidative properties, and, for this reason, they have been used in inflammatory animal models or in clinical trials. Despite intensive investigation on terrestrial polyphenols, marine polyhenols have been less explored. While algae are commonly consumed in Asia as a food, in Western countries their use is very scarce. Therefore, consumption of polyphenols from marina algae could provide health benefits to obese people, whose numbers have increased tremendously in Europe and America. Moreover, their dietary use can also be extended to patients with chronic inflammatory disease, even including bowel disease. Therefore, these compounds or their structural analogs have the potential to be used as nutraceuticals in different clinical settings.

On these bases, the aims of the proposed Special Issue will be to illustrate marine polyphenols from three different points of view: (1) Description of the chemical structures of marine flavonoids and their comparison with terrestrial polyphenols, e.g., flavonoids from green tea, red grape, berry, cocoa, etc.; (2) description of their effects on in vitro models with special reference to the immune response; and (3) the effects of marine polyphenols on in vivo models or in clinical trials in terms of their anti-inflammatory and anti-oxidative capacities.

This Special Issue will be structured in a way to encompass both biological and clinical applications of marine polyphenols and should attract many readers. It may also promote knowledge of these natural products, even among people from geographic areas where polyphenols are assumed through fruits, vegetables and cereals. Given this, new studies based on the comparison between terrestrial and marine polyphenols in terms of their structure and clinical application may be generated, thus giving new impetus to this field of research.

Prof. Emilio Jirillo
Guest Editor

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