Novel Strategies for Diagnosis and Treatment of Heart Failure

Dear Colleagues,

Heart failure (HF) is a complex clinical syndrome that may be caused by a number of structural and/or functional cardiac abnormalities. Developing the condition will result in a reduced cardiac output and/or elevated intracardiac pressures at rest or during stress.

As a growing public health problem with a prevalence of 1–2% in the adult population, HF impacts heavily on patient survival, quality of life and health care costs. Despite the advancement in medical and device therapy, the management of HF remains a challenge.

The early and accurate diagnosis of HF, paired with proper identification of the underlying etiology, is of great importance for treatment and ultimately for enhancing prognosis and quality of life.

In particular, HF is one of the most severe clinical manifestations of classical and novel cancer therapies and can occur either acutely or after years of treatment. As suggested by recent cardio-oncology guidelines, prevention and early detection have become a priority.

Current clinical strategies for the management of patients with HF are heavily based on information provided by multimodality cardiovascular imaging that allows non-invasive morphological and functional assessment, tissue characterization, blood flow and perfusion evaluation.

Therefore, further research on cardiovascular imaging may substantially contribute to the early etiological diagnosis, prognostic stratification and treatment management of HF patients.

In this Special Issue, we invite experts in the field of HF and Cardioncology to submit their original research and/or systematic reviews covering one or more of the following topics:

1. Recent advances in heart failure treatment;
2. Expert reviews on the latest and ongoing RCTs on HF medications;
3. Multimodality imaging as an approach to individualize treatment, guide long-term management, and stratify prognosis in HF;
4. Multimodality imaging for assessment of specific HF etiologies;
5. Multimodality imaging in risk stratification, early detection of cardiovascular sequelae of cancer and related therapies.

Dr. Carla Contaldi
Dr. Giuseppe Pacileo
Guest Editors

Manuscript Submission Information

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• heart failure treatment
• HFrEF
• HFpEF
• cardiovascular pharmacotherapy
• multimodality cardiovascular imaging
• echocardiography
• cardiac magnetic resonance
• cardioncology
• cardiotoxicity