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Medicina
Special Issues
Coronary Syndrome: Prevention and Management
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Coronary Syndrome: Prevention and Management

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (30 July 2024) | Viewed by 1491

Special Issue Editor

Dr. Cristian Mornos

E-Mail Website
Guest Editor
Cardiology Department, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Interests: cardiovascular disease; coronary syndrome; cardiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are currently working on a Special Issue of Medicina focusing on the prevention and management of coronary syndrome. Despite remarkable progress in recent decades, coronary artery disease still represents a major public health issue, with a huge impact in terms of mortality, morbidity and the quality of life. Great research efforts are still necessary to improve the prognosis of this disease. The exploration of new risk factors may contribute to medical management and health care. Circulating biomarkers involved in the pathogenesis of coronary artery disease have the potential to detect the disease at early stages: biochemical (proteins), inflammatory, epigenetic (ncRNA, miRNA) and transcriptional markers (gene expression). In parallel, new imaging diagnostic tools are being developed to allow for less invasive and more widely applicable diagnoses. Nowadays, imaging is rapidly evolving due to the many applications of artificial intelligence, modern magnetic resonance techniques and computer tomographic imaging. We want to understand diagnostic decisions, derive treatment-guiding and prognostic information, and assess treatment responses from primary prevention and pharmacotherapy to invasive management. We aim to offer readers a snapshot of the latest advances in the field and overview the most intriguing challenges ahead and expected developments that may impact our daily clinical practice. We would be very happy to receive your contribution, and we look forward to receiving your input for this exciting project.

Dr. Cristian Mornos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • risk factors
  • coronary pathophysiology
  • biomarkers
  • non-invasive imaging
  • prognosis
  • pharmacotheraphy
  • interventional management

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Published Papers (1 paper)

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Research

15 pages, 3016 KiB  
Article
Short-Term Changes in Weather Conditions and the Risk of Acute Coronary Syndrome Hospitalization with and without ST-Segment Elevation: A Focus on Vulnerable Subgroups
by Andreea-Alexandra Rus, Mihai-Andrei Lazăr, Romeo Negrea, Alina-Ramona Cozlac, Cristina Văcărescu, Raluca Şoşdean, Silvia-Ana Luca, Dan Gaiţă and Cristian Mornoş
Medicina 2024, 60(3), 454; https://doi.org/10.3390/medicina60030454 - 9 Mar 2024
Viewed by 1152
Abstract
Background and Objectives: Acute coronary syndrome (ACS), a prevalent global cardiovascular disease and leading cause of mortality, is significantly correlated with meteorological factors. This study aims to analyze the impact of short-term changes in meteorological factors on the risk of ACS, both [...] Read more.
Background and Objectives: Acute coronary syndrome (ACS), a prevalent global cardiovascular disease and leading cause of mortality, is significantly correlated with meteorological factors. This study aims to analyze the impact of short-term changes in meteorological factors on the risk of ACS, both with and without ST-segment elevation, and to identify vulnerable subgroups. Materials and Methods: Daily ACS admissions and meteorological variables were collected from October 2016 to December 2021. A generalized linear model (GLM) with a Poisson distribution was employed to examine how short-term fluctuations in meteorological parameters influence ACS hospitalizations. Subgroup analyses were conducted to identify the populations most vulnerable to climate change. Results: Multiple regression analyses showed that short-term fluctuations in atmospheric pressure (≥10 mbar) and air temperature (≥5 °C) seven days prior increased the number of ACS hospitalizations by 58.7% (RR: 1.587; 95% CI: 1.501–1.679) and 55.2% (RR: 1.552; 95% CI: 1.465–1.644), respectively, notably impacting ST-segment elevation myocardial infarctions (STEMIs). The least pronounced association was observed between the daily count of ACS and the variation in relative air humidity (≥20%), resulting in an 18.4% (RR: 1.184; 95% CI: 1.091–1.286) increase in the risk of hospitalization. Subgroup analysis revealed an increased susceptibility among men and older adults to short-term variations in weather parameters. Conclusions: The findings indicate that short-term changes in weather conditions are associated with an increased risk of ACS hospitalizations, particularly STEMIs. Male and older adult patients exhibit heightened susceptibility to variations in climatic factors. Developing effective preventive strategies is imperative to alleviate the adverse consequences of these environmental risk factors. Full article
(This article belongs to the Special Issue Coronary Syndrome: Prevention and Management)
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