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Medicina
Special Issues
Chronic Respiratory Diseases: Updates on Pathophysiology, Symptoms, Diagnosis and Treatment
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Chronic Respiratory Diseases: Updates on Pathophysiology, Symptoms, Diagnosis and Treatment

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Pulmonary".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 497

Special Issue Editors

Dr. Marcin Kurowski

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Guest Editor
Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland
Interests: asthma; exercise-induced bronchoconstriction; allergic rhinitis; food allergy; urticaria and angioedema; molecular allergy diagnostics; biological treatment
Special Issues, Collections and Topics in MDPI journals
Dr. Laura Malinauskienė

E-Mail Website
Guest Editor
1. Department of Pulmonology and Allergology, Vilnius University Hospital Santaros Klinikos, Santariskiu 2, LT-08661 Vilnius, Lithuania
2. Faculty of Medicine, Vilnius University, M.K. Ciurlionio 21/27, LT-03101 Vilnius, Lithuania
Interests: asthma; allergic rhinitis; drug allergy; molecular allergy diagnostics; biological treatment; primary and secondary immunodeficiencies; urticaria and angioedema; anaphylaxis
Dr. Corrado Pelaia

E-Mail Website
Guest Editor
Department of Health Sciences, University “Magna Græcia” of Catanzaro, Catanzaro, Italy
Interests: asthma; lung immunology; COPD and COVID-19
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chronic respiratory diseases are posing a considerable burden to society, patients, caretakers and medical professionals. In addition to the well-known contributing factors, air pollution and climate change have emerged as new reasons for the increase in the frequency of diagnoses and exacerbations of chronic respiratory conditions.

Simultaneously, novel aspects of respiratory pathophysiology are being described, new management modalities introduced, and treatment paradigms revisited and modified.

In this context, we are honored to invite you to submit your valuable contribution to the new Special Issue of Medicina, aiming to provide a comprehensive insight into the novel trends in research and clinical management of chronic respiratory diseases, including, but not limited to, asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, chronic rhinosinusitis, allergic rhinoconjunctivitis and other conditions.

Reviews, original research, case reports and case series descriptions, as well as real-world data presentations are contribution formats that we invite you to submit.

We encourage you to be part of this fascinating project!

Dr. Marcin Kurowski
Dr. Laura Malinauskienė
Dr. Corrado Pelaia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • asthma
  • COPD
  • obstructive lung diseases
  • chronic rhinosinusitis with/without polyps
  • allergic rhinitis
  • allergic rhinoconjunctivitis
  • lower airways
  • upper airways

Published Papers (1 paper)

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Research

9 pages, 1131 KiB  
Article
Phenotype and Clinicoradiological Differences in Multifocal and Focal Bronchiectasis
by Jelena Jankovic, Aleksandar Jandric, Natasa Djurdjevic, Dragan Vukosavljevic, Zlatan Bojic, Andrej Zecevic and Mihailo Stjepanovic
Medicina 2024, 60(5), 795; https://doi.org/10.3390/medicina60050795 - 10 May 2024
Viewed by 307
Abstract
Introduction: Bronchiectasis is a chronic progressive respiratory disease characterized by permanent dilatation of the bronchi. It is a complex condition with numerous different etiologies, co-morbidities, and a heterogeneous presentation. As we know, there is a lack of studies that describe the differences and [...] Read more.
Introduction: Bronchiectasis is a chronic progressive respiratory disease characterized by permanent dilatation of the bronchi. It is a complex condition with numerous different etiologies, co-morbidities, and a heterogeneous presentation. As we know, there is a lack of studies that describe the differences and compare the characteristics between focal and multifocal bronchiectasis. The aim of this study is to identify differences in clinical characteristics presentation, severity or distribution in focal and multifocal bronchiectasis, and prognostic implications. Methods: 126 patients with computed tomography (CT)-verified bronchiectasis were enrolled. Baseline characteristics that included age, sex, smoking history, and respiratory symptoms were recorded, with special attention paid to hemoptysis appearance, body mass index, and comorbidities. The type of bronchiectasis determined by CT scan and the modified Reiff scores indicating radiological severity were recorded. Patients were divided in two groups (I is focal and II is multifocal). Results: There were no statistically significant differences in age, smoking status, comorbidity, and BMI between the two groups. Multifocality was associated with a significantly higher proportion of females (p = 0.014), the rate of hemoptysis (p = 0.023), and the number of hospitalizations, but not of exacerbations and prevalence of immunodeficiency (p = 0.049). Significantly, a high number of subjects with multifocality had bronchiectasis of moderate severity, and post-infective and asthma-associated phenotypes were the dominant in this group. Unexpectedly, the cystic and varicose radiological phenotype (which need more time to develop) were more dominant in the focal group. The cylindrical phenotype was equally observed in the multifocal and focal groups. Conclusions: Our study suggests that multifocality is not related to age, number of exacerbations, or radiological phenotype, but it seems to be associated with the clinical post-infective phenotype, immunodeficiency, frequent hospitalizations, and severity. Thus, the presence of multifocal bronchiectasis may act as a biomarker of severity and poor outcomes in these patients. Full article
(This article belongs to the Special Issue Chronic Respiratory Diseases: Updates on Pathophysiology, Symptoms, Diagnosis and Treatment)
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