Metabolism and Immunomodulation in Liver Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 143
Special Issue Editors
Interests: hepatobiliary and gastrointestinal diseases; immunometabolsim; cell death and cellular senescence
Special Issue Information
Dear Colleagues,
Liver, the largest organ in the human body, is considered to be a determent in variable biological processes, including metabolism, immunity, and homeostasis. Hepatic cells are composed of parenchymal cells (hepatocytes, cholangiocytes, and liver sinusoidal endothelial cells) and non-parenchymal cells (kupffer cells, hepatic stellate cells, infiltrating immune cells, etc.). A complex of immune and metabolic regulation exists in the liver, maintaining biological functions and responding actively to homeostatic disturbances. In liver diseases, each specific cell–cell interaction can influence disease progressions, such as liver regeneration, ductular reaction, fibrosis, inflammation, and carcinogenesis. Notably, liver inflammation is a hallmark of progressive liver diseases. Furthermore, immunomodulation, initiated by cellular interactions and secretome, serves both the fundamental roles and main challenges in the management of liver diseases.
In this Special Issue, we will try to summarize advances in cellular interactions and immunomodulation in liver diseases. We also intend to promote investigations on the immune and metabolism landscape and its implications in liver pathomechanisms, e.g., by revealing multicellular crosstalk, identifying key factors, and developing novel technics.
Dr. Hanyang Liu
Dr. Peiyuan Yin
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- liver diseases
- cellular interactions
- immunomodulation
- hepatic metabolism
- hepatic fibrosis
- hepatic carcinogenesis
- ductular reaction
- cell fates
- secretome
