Molecular Mechanisms in Cancer, Cardiovascular and Metabolic Diseases: Potential Therapies and Treatments

Dear Colleagues,

Cardiovascular diseases and cancers are the main causes of death worldwide, and recently it has been reported that cardiovascular and metabolic diseases favor the development of cancers. In recent years, several studies have shown various deregulated cellular and molecular mechanisms favoring pathophysiological processes such as inflammation, increase in reactive oxygen species, apoptosis and fibrosis inducing the development and progression of these diseases, including many of these molecular mechanisms are regulated by non-coding RNAs such as microRNAs, circRNAs and long-non-coding RNAs. Understanding these mechanisms will enable the creation of new treatments, and these molecules can serve as new biomarkers for diagnosis and targeted gene therapy. Therefore, this Special Edition is focused on articles that can elucidate new signaling pathways deregulated in cancer, cardiovascular and metabolic diseases, as well as articles that evaluate the response to treatments for these diseases. We welcome submissions of original pre-clinical and clinical articles, reviews, mini-reviews and letters.

Dr. Alex Cleber Improta-Caria
Guest Editor

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• molecular mechanisms
• cancer
• cardiovascular diseases
• metabolic diseases
• treatments