Integrative Metabolomic Biomarkers for Neurodegeneration

Dear Colleagues,

The biomarkers of neurodegeneration have played an increasingly important role in predicting the disease risk, establishing a diagnosis, predicting the treatment response, monitoring the disease progression, serving as drug targets, and enabling prognosis determination. Furthermore, the discovery of new biomarkers can shed light on the physiological mechanisms of neurodegeneration. The search for neurodegenerative biomarkers is actively ongoing. It is hoped that easily clinically assessable biomarkers will facilitate the earlier diagnosis of neurodegeneration, leading to improved therapies.

Some examples of biomarker categories include genetic information, protein and hormone levels, cellular characteristics, metabolomics, and medical imaging results. The connection between biomarkers and biological phenomena is strengthened when integrated with multi-omics data. Furthermore, the introduction of machine learning to integrative multi-omics data has helped to uncover novel biomarkers for disease.

This Special Issue is focused on integrative metabolomic biomarkers for neurodegenerative diseases. The possible topics include the use of integrative metabolomics to discover novel metabolite biomarkers, to describe new insights into current metabolic biomarkers, to propose novel approaches for improving the quality of data and integration of metabolomics, and to leverage metabolomic biomarkers as drug targets.

Dr. Robert Logan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• integrative metabolomics
• multi-omics
• biomarkers
• neurodegeneration
• bioinformatics
• machine learning
• Parkinson’s disease
• Alzheimer’s disease