Lipidomics in Health and Disease
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Lipid Metabolism".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 765
Special Issue Editor
Interests: metabolomics; lipidomics of diseases; disease models
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This is an invitation to submit research articles and reviews regarding the ever-increasing utility of lipidomics in medical and veterinary research.
Lipidomics is a specialized subfield of metabolomics, with research in this area expanding at a rapid rate. This includes basic and clinical research efforts. As a result, there are a number of potential lipid biomarkers that are under intense study in the fields of oncology, infectious diseases, neurology, and psychiatry. These are biomarkers of disease, of disease progression, and of disease response to therapy. In addition, biomarkers offer the potential to stratify patient subgroups and define new molecular targets for therapeutic intervention. Lipids are multifunctional in that they serve as energy stores, as structural biomolecules in membranes, and in signal transduction pathways. In addition, there are highly specialized lipids that serve unique compartmentalized biological functions.
Analytical advancements, particularly electrospray ionization high-resolution mass spectrometry (ESI-HR-MS), have enabled sampling across a broad domain of these lipids utilizing direct-flow analyses and the introduction of samples by chromatographic methods. Tandem mass spectrometry is also essential for validating the structures of the monitored lipids.
In summary, lipidomics is a fast-paced research field in which HR-MS and mass spectrometric lipid imaging further our knowledge of lipid dynamics, the cellular ultrastructure of lipid pools, and lipid alterations in disease. Decades of exciting research lie ahead for this field.
With this invitation, we solicit research related to basic research, lipidomics methodology, clinical diagnostics, and clinical therapies. In particular, we invite reviews of alternate analytical strategies, data validation, and available lipid databases to be submitted.
Prof. Dr. Paul Wood
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lipidomics
- high-resolution mass spectrometry
- lipid derivatization
- lipid chromatography
- diagnostics
- therapeutics
