Advanced Metals and Alloys for Biomedical Applications

A special issue of Metals (ISSN 2075-4701).

Deadline for manuscript submissions: closed (20 November 2020) | Viewed by 4252

Special Issue Editor


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Guest Editor
Department of Advanced Materials and Technologies, Faculty of Advanced Technologies and Chemistry, Military University of Technology, Gen. S. Kaliskiego 2, 00-908 Warsaw, Poland
Interests: microstructural characterization; nonferrous alloys (Al, Ti, Mg, etc.); intermetallics; additive manufacturing; hydrogen storage
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Special Issue Information

Dear Colleagues,

Metals and their alloys have been used as implants for almost 125 years, when in 1895, for the first time, a metal plate was introduced for bone fracture fixation. Because of their use as implant materials, they must meet the requirements of biocompatibility, bone conductivity, and bioactivity. Hence, surface modifications are required. Moreover, depending on the application, metals and implantation alloys must have excellent toughness, elasticity, rigidity, strength and resistance to fracture, wear and corrosion resistance, and even the shape memory effect.

All of these properties of implant materials (of metals and alloys) are significantly affected by their technology and resulting microstructure, including their phase composition, grain shape and size, grain boundary distribution, dislocation density, dispersed particles and solutes, internal stresses, and so on. Therefore, the studies on the relationships between technology, microstructure, and implant properties are of a great practical importance.

The most known and most commonly used metals for implants are stainless steel, CoCr alloys, and Ti alloys. Moreover, noble metals and alloys such as Au, Ag, and Pt, and their alloys are often used in dentistry. Other metals used for implants include tantalum (Ta), amorphous alloys, and biodegradable metals. Hence, the effort put into searching for new implant materials and modifying existing implant materials is so important for biomedical applications.

The aim of this Special Issue is to present the latest achievements in the technology, structure development, surface modification, and properties of various metallic materials for implants. In conclusion, it is my pleasure to invite all researchers from the community of metals and alloys for biomedical application to submit a manuscript in the field for this Special Issue.

Prof. Dr. Tomasz Czujko
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Titanium alloys
  • Stainless steel
  • CoCr alloys
  • Dental alloys
  • Biodegradable alloys
  • Structure
  • Mechanical properties
  • Corrosion resistance
  • Wear resistance
  • Surface modification

Published Papers (1 paper)

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Research

20 pages, 8958 KiB  
Article
In Vitro Bone Cell Behavior on Porous Titanium Samples: Influence of Porosity by Loose Sintering and Space Holder Techniques
by Ana Civantos, Mercè Giner, Paloma Trueba, Sheila Lascano, María-José Montoya-García, Cristina Arévalo, María Ángeles Vázquez, Jean Paul Allain and Yadir Torres
Metals 2020, 10(5), 696; https://doi.org/10.3390/met10050696 - 25 May 2020
Cited by 25 | Viewed by 3257
Abstract
A great variety of powder metallurgy techniques can produce biomimetic porous titanium structures with similar mechanical properties to host bone tissue. In this work, loose sintering and space holder techniques, two frequently used metallurgical techniques, are compared to evaluate the influences of porosity [...] Read more.
A great variety of powder metallurgy techniques can produce biomimetic porous titanium structures with similar mechanical properties to host bone tissue. In this work, loose sintering and space holder techniques, two frequently used metallurgical techniques, are compared to evaluate the influences of porosity (content, size, morphology and wall roughness), mechanical properties (stiffness and yield strength) and in-vitro cellular responses (adhesion and proliferation of myoblasts and osteoblasts). These comparisons are made to achieve the best balance between biomechanical and bifunctional behavior of a partial porous implant for cortical bone replacement. Cell adhesion (filopodia presence) and spreading were promoted on both porous surfaces and fully dense substrates (non-porous control surfaces). Porous scaffold samples designed using 50 vol.% NaCl space holder technique had an improved bioactive response over those obtained with the loose sintering technique due to higher roughness and scaffold pore diameter. However, the presence of large and heterogeneous pores compromises the mechanical reliability of the implant. Considering both scenarios, the substrates obtained with 40 vol.% NH4HCO3 and pore size ranges between 100 and 200 μm provide a balanced optimization of size and strength to promote in-vitro osseointegration. Full article
(This article belongs to the Special Issue Advanced Metals and Alloys for Biomedical Applications)
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