Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.4
4.5
Journals
Microorganisms
Special Issues
Exploring the Unique Natural Product Potential of Cyanobacteria
share announcement

Exploring the Unique Natural Product Potential of Cyanobacteria

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Environmental Microbiology".

Deadline for manuscript submissions: closed (30 December 2023) | Viewed by 4374

Special Issue Editors

Prof. Dr. Valeria Costantino

E-Mail Website
Guest Editor
Department of Pharmacy, University of Naples Federico II, Via Montesano 149, 80131 Naples, Italy
Interests: isolation and stereostructural elucidation of new leads compounds in anti-inflammatory and anti-cancer drug discovery; exploration of the QQ and the QS system in bacteria symbiotic with sponges with the goal to create novel leads in antibacterial drug discovery; cyanobacteria as source of novel lead compounds and toxins
Special Issues, Collections and Topics in MDPI journals
Dr. Germana Esposito

E-Mail Website
Guest Editor
The Blue Chemistry Lab, Department of Pharmacy, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy
Interests: natural products; molecular networking; cyanobacteria; structural determination; LC-MS; NMR
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cyanobacteria, photosynthetic microorganism, are spread out in a large array of environments, from tropical areas to extremely cold waters, in marine waters, as well as in freshwaters. Cyanobacteria are well known to produce secondary metabolites, bioactive natural products with interesting pharmacological properties, either toxins, named cyanotoxins, that can be found in the food chain, raising health problems to the population.

In this special issue, we wish to collect papers reporting novel class of cyano-metabolites or cyanotoxins, having biological properties or toxicity. Moreover, we wish to collect report on cyano blooms around the world. With the aim to support woman scientists, we deeply welcome contributions submitted by women corresponding authors or first name authors

Prof. Dr. Valeria Costantino
Dr. Germana Esposito
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cyanobacteria
  • cyanotoxin
  • cyanometabolite
  • cyanobloom
  • microorganism
  • marine bacteria
  • secondary metabolites
  • bioactivity
  • toxicity

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

15 pages, 105091 KiB  
Article
Gold Nanoparticles Bioproduced in Cyanobacteria in the Initial Phase Opened an Avenue for the Discovery of Corresponding Cerium Nanoparticles
by Melanie Fritz, Xiaochen Chen, Guifang Yang, Yuancai Lv, Minghua Liu, Stefan Wehner and Christian B. Fischer
Microorganisms 2024, 12(2), 330; https://doi.org/10.3390/microorganisms12020330 - 04 Feb 2024
Viewed by 762
Abstract
The production of isolated metallic nanoparticles with multifunctionalized properties, such as size and shape, is crucial for biomedical, photocatalytic, and energy storage or remediation applications. This study investigates the initial particle formations of gold nanoparticles (AuNPs) bioproduced in the cyanobacteria Anabaena sp. using [...] Read more.
The production of isolated metallic nanoparticles with multifunctionalized properties, such as size and shape, is crucial for biomedical, photocatalytic, and energy storage or remediation applications. This study investigates the initial particle formations of gold nanoparticles (AuNPs) bioproduced in the cyanobacteria Anabaena sp. using high-resolution transmission electron microscopy images for digital image analysis. The developed method enabled the discovery of cerium nanoparticles (CeNPs), which were biosynthesized in the cyanobacteria Calothrix desertica. The particle size distributions for AuNPs and CeNPs were analyzed. After 10 h, the average equivalent circular diameter for AuNPs was 4.8 nm, while for CeNPs, it was approximately 5.2 nm after 25 h. The initial shape of AuNPs was sub-round to round, while the shape of CeNPs was more roundish due to their amorphous structure and formation restricted to heterocysts. The local PSDs indicate that the maturation of AuNPs begins in the middle of vegetative cells and near the cell membrane, compared to the other regions of the cell. Full article
(This article belongs to the Special Issue Exploring the Unique Natural Product Potential of Cyanobacteria)
►▼ Show Figures

Figure 1

14 pages, 1857 KiB  
Article
Harnessing Cyanobacteria’s Bioactive Potential: A Sustainable Strategy for Antioxidant Production
by Teresa De Rosa, Maria Ponticelli, Roberta Teta, Vittorio Carlucci, Luigi Milella, Germana Esposito and Valeria Costantino
Microorganisms 2024, 12(1), 175; https://doi.org/10.3390/microorganisms12010175 - 16 Jan 2024
Viewed by 692
Abstract
Unsaturated diacylglycerols are a class of antioxidant compounds with the potential to positively impact human health. Their ability to combat oxidative stress through radical scavenger activity underscores their significance in the context of preventive and therapeutic strategies. In this paper we highlight the [...] Read more.
Unsaturated diacylglycerols are a class of antioxidant compounds with the potential to positively impact human health. Their ability to combat oxidative stress through radical scavenger activity underscores their significance in the context of preventive and therapeutic strategies. In this paper we highlight the role of Anabaena flos-aquae as a producer of unsaturated mono and diacylglycerols, and then demonstrate the antioxidant activity of its methanolic extract, which has as its main components a variety of acylglycerol analogues. This finding was revealed using a sustainable strategy in which the One Strain Many Compounds (OSMAC) cultivation in microscale was coupled with a bioinformatic approach to analyze a large dataset of mass spectrometry data using the molecular networking analyses. This strategy reduces time and costs, avoiding long and expensive steps of purification and obtaining informative data on the metabolic composition of the extracts. This study highlights the role of Anabaena as a sustainable and green source of novel bioactive compounds. Full article
(This article belongs to the Special Issue Exploring the Unique Natural Product Potential of Cyanobacteria)
►▼ Show Figures

Figure 1

13 pages, 3389 KiB  
Article
Recoverability of Microcystis aeruginosa and Pseudanabaena foetida Exposed to a Year-Long Dark Treatment
by Hongyu Yan and Mudalige Don Hiranya Jayasanka Senavirathna
Microorganisms 2023, 11(11), 2760; https://doi.org/10.3390/microorganisms11112760 - 13 Nov 2023
Viewed by 883
Abstract
Cyanobacteria are a significant primary producer and pioneer species that play a vital role in ecological reconstruction, especially in aquatic environments. Cyanobacteria have excellent recovery capacity from significant stress exposure and are thus suggested as bioreserves, even for space colonization programs. Few studies [...] Read more.
Cyanobacteria are a significant primary producer and pioneer species that play a vital role in ecological reconstruction, especially in aquatic environments. Cyanobacteria have excellent recovery capacity from significant stress exposure and are thus suggested as bioreserves, even for space colonization programs. Few studies have been conducted on the recovery capacity after experiencing stress. Long-duration darkness or insufficient light is stressful for photosynthetic species, including cyanobacteria, and can cause chlorosis. Cyanobacterial recovery after extensive exposure to darkness has not yet been studied. In this experiment, Microcystis aeruginosa and Pseudanabaena foetida were subjected to a year-long darkness treatment, and the change in recovery capacity was measured in monthly samples. Cyanobacterial growth, chlorophyll-a concentration, oxidative stress, and photosynthetic capacity were evaluated. It was found that the rapid recovery capacity of the two species remained even after one year of darkness treatment. However, the H2O2 content of recovered samples of both M. aeruginosa and P. foetida experienced significant changes at six–seven months, although the photosynthetic capacity of both cyanobacteria species was maintained within the healthy range. The chlorophyll-a and carotenoid content of the recovered samples also changed with increasing darkness. The results showed that long-term dark treatment had time-dependent effects but different effects on M. aeruginosa and P. foetida. However, both cyanobacteria species can recover rapidly after one year of dark treatment. Full article
(This article belongs to the Special Issue Exploring the Unique Natural Product Potential of Cyanobacteria)
►▼ Show Figures

Figure 1

13 pages, 3187 KiB  
Article
Cellulose Synthase in Atacama Cyanobacteria and Bioethanol Production from Their Exopolysaccharides
by Alexandra Galetović, Gabriel Peña, Nicole Fernández, Milton Urrutia, Nataly Flores, Benito Gómez-Silva, Jocelyne Di Ruggiero, Carolina Shene and Mariela Bustamante
Microorganisms 2023, 11(11), 2668; https://doi.org/10.3390/microorganisms11112668 - 30 Oct 2023
Viewed by 1061
Abstract
Cyanobacteria produce exopolysaccharides (EPSs) as an adaptative mechanism against ultraviolet radiation and desiccation. Cellulose is present in the extracellular polymeric substance in some cyanobacteria genera and it has been proposed as a raw material for biofuel production. The goal of this work was [...] Read more.
Cyanobacteria produce exopolysaccharides (EPSs) as an adaptative mechanism against ultraviolet radiation and desiccation. Cellulose is present in the extracellular polymeric substance in some cyanobacteria genera and it has been proposed as a raw material for biofuel production. The goal of this work was to evaluate the cellulose presence in EPS of Atacama cyanobacteria strains and its use as an alternative and innovative biological source to produce bioethanol. The presence of cellulose was evaluated using techniques of molecular biology, bioinformatics, and electronic microscopy. The conserved motif D,D,D,35QXXRW, characteristic of processive β-glycosyltransferase in all cellulose-producing organisms, was identified in the genome of the LLA-10 strain. This is evidence that cellulose synthase in the LLA-10 strain is a functional enzyme. EPS from Atacama cyanobacteria was hydrolyzed by β-glucosidases (cellobiase and cellulase) and the released glucose was yeast-fermented to ethanol. Ethanol production reached 172.69 ± 0.02 mg ethanol/g EPS after 48 h of incubation. These results are the first step in the evaluation of EPS produced by native cyanobacteria isolated from northern Chile for future biotechnological applications such as the production of bioethanol. Full article
(This article belongs to the Special Issue Exploring the Unique Natural Product Potential of Cyanobacteria)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop