Natural Terpenoid Alkaloids: Extraction, Phytochemistry Analysis and Human Health
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 576
Special Issue Editor
2. Institute for Translational Medicine, Faculty of Medicine, University of Pécs, Szigeti út 12, 7624 Pécs, Hungary
Interests: phytochemistry; pharmacognosy; phytotherapy; phytochemical analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diterpene alkaloids (DA) have been isolated primarily from the Ranunculaceae species. To date, several hundred such compounds are known, and many of these alkaloids have remarkable biological effects. Several DA-containing plants are known to be toxic plants. However, some of these in low doses or after careful processing have been applied in traditional medicine, especially in Asia.
Their inhibitory or agonist effect on different ion channels is closely related to the toxic and pharmacologically useful effects of DAs. If their appropriate selective affinity to pharmacological targets is evident, DAs can be used as medicines. Certain compounds that comprise part of evidence-based medicine in their use as antiarrhythmic drugs and several other alkaloids are under investigation for their effects on the central nervous system.
The goal of this Special Issue is to provide an overview of the current research results on DAs, including their isolation, structure elucidation, semisynthetic modifications, and pharmacological investigations thereof.
Dr. Dezső Csupor
Guest Editor
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Keywords
- diterpene alkaloid
- norditerpene alkaloid
- Ranunculaceae
- vardiovascular
- central nervous system
