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Molecules
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Advances in Nanomaterials for Bioapplications and Water Treatment
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Advances in Nanomaterials for Bioapplications and Water Treatment

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 8074

Special Issue Editor

Dr. Ana Luísa Daniel da Silva

E-Mail Website
Guest Editor
CICECO-Aveiro Institute of Materials, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: nanoparticles; nanocomposites; organic-inorganic hybrids; nanomaterials; surface modification; water treatment; magnetic separation; biomedical applications; environmental nanotechnology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanomaterials, in addition to their small size and increased surface area, possess unique physicochemical properties that enable specific applications that cannot be performed by either molecular species or bulk materials. In the past few years, we have witnessed significant advancements that demonstrate the advantages of colloidal nanomaterials for biomedical and water treatment applications. The intrinsic optical, magnetic, and electrical properties of inorganic nanoparticles can be tuned by engineering the size and shape of the inorganic core towards sensitive imaging in medicine and achieving the most effective therapeutic effects. The nanomaterials possessing specific surface chemistry and wettability are of high relevance for water treatment and contaminated site remediation. This Special Issue on ”Advances in Nanomaterials for Bioapplications and Water Treatment” aims to address the main successes and challenges in developing functional nanomaterials, not only regarding the chemical synthesis, surface functionalization, and characterization, but also in designing their functional properties for practical applications. Some examples of the topics within the scope of this Issue include the chemistry of nanosorbents, photocatalysis for water treatment, nanocarriers in medical diagnostics and drug delivery, and nanoenabled bioseparation.

Dr. Ana Luísa Daniel da Silva
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanosorbents
  • photocatalysts
  • nanomedicine
  • nanocarriers
  • drug delivery
  • diagnosis
  • hyperthermia
  • bioseparation

Published Papers (2 papers)

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Research

14 pages, 2435 KiB  
Article
Potential Decontamination of Drinking Water Pathogens through k-Carrageenan Integrated Green Bottle Fly Bio-Synthesized Silver Nanoparticles
by M. A. Abu-Saied, Mohamed Elnouby, Tarek Taha, Muhammad El-shafeey, Ali G. Alshehri, Saad Alamri, Huda Alghamdi, Ali Shati, Sulaiman Alrumman, Mohamed Al-Kahtani and Mahmoud Moustafa
Molecules 2020, 25(8), 1936; https://doi.org/10.3390/molecules25081936 - 22 Apr 2020
Cited by 8 | Viewed by 2609
Abstract
The wide distribution of infections-related pathogenic microbes is almost related to the contamination of food and/or drinking water. The current applied treatments face some limitations. In the current study, k-carrageenan polymer was used as supporting material for the proper/unreleased silver nanoparticles that showed [...] Read more.
The wide distribution of infections-related pathogenic microbes is almost related to the contamination of food and/or drinking water. The current applied treatments face some limitations. In the current study, k-carrageenan polymer was used as supporting material for the proper/unreleased silver nanoparticles that showed strong antimicrobial activity against six pathogenic bacteria and yeast. The bio-extract of the pupa of green bottle fly was used as the main agent for the synthesis of silver nanoparticles. The qualitative investigation of biologically synthesized silver nanoparticles was determined using UV-Vis spectrophotometric analysis; however, the size of nanoparticles was in range of 30–100 nm, as confirmed by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and particle size analyzer. The proper integration of silver nanoparticles into the polymeric substrate was also characterized through fourier transform infrared (FT-IR), thermogravimetric analysis (TGA), SEM, and tensile strength. The antimicrobial activity of k-carrageenan/silver nanoparticles against Gram positive, Gram negative, and yeast pathogens was highly effective. These results indicate the probable exploitation of the polymeric/nanoparticles composite as an extra stage in water purification systems in homes or even at water treatment plants. Full article
(This article belongs to the Special Issue Advances in Nanomaterials for Bioapplications and Water Treatment)
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19 pages, 4043 KiB  
Article
Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy
by João Nogueira, Sofia F. Soares, Carlos O. Amorim, João S. Amaral, Cláudia Silva, Fátima Martel, Tito Trindade and Ana L. Daniel-da-Silva
Molecules 2020, 25(2), 333; https://doi.org/10.3390/molecules25020333 - 14 Jan 2020
Cited by 41 | Viewed by 5118
Abstract
Doxorubicin is one of the most widely used anti-cancer drugs, but side effects and selectivity problems create a demand for alternative drug delivery systems. Herein we describe a hybrid magnetic nanomaterial as a pH-dependent doxorubicin release carrier. This nanocarrier comprises magnetic iron oxide [...] Read more.
Doxorubicin is one of the most widely used anti-cancer drugs, but side effects and selectivity problems create a demand for alternative drug delivery systems. Herein we describe a hybrid magnetic nanomaterial as a pH-dependent doxorubicin release carrier. This nanocarrier comprises magnetic iron oxide cores with a diameter of 10 nm, enveloped in a hybrid material made of siliceous shells and ĸ-carrageenan. The hybrid shells possess high drug loading capacity and a favorable drug release profile, while the iron oxide cores allows easy manipulation via an external magnetic field. The pH responsiveness was assessed in phosphate buffers at pH levels equivalent to those of blood (pH 7.4) and tumor microenvironment (pH 4.2 and 5). The nanoparticles have a loading capacity of up to 12.3 wt.% and a release profile of 80% in 5 h at acidic pH versus 25% at blood pH. In vitro drug delivery tests on human breast cancer and non-cancer cellular cultures have shown that, compared to the free drug, the loaded nanocarriers have comparable antiproliferative effect but a less intense cytotoxic effect, especially in the non-cancer cell line. The results show a clear potential for these new hybrid nanomaterials as alternative drug carriers for doxorubicin. Full article
(This article belongs to the Special Issue Advances in Nanomaterials for Bioapplications and Water Treatment)
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