Anticancer Drug Discovery and Development II
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 22343
Special Issue Editors
Interests: MRI; MRS; cancer; biochemistry; drug delivery systems
Special Issues, Collections and Topics in MDPI journals
Interests: photochemistry; photobiology; medical chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Photodynamic therapy, which uses a photosensitizer, light and oxygen to kill cancer cells, is an adjuvant therapy that can be applied following the removal of a tumor to kill residual cancer cells on the resection border. Despite the use of traditional treatment, which may include adjuvant photodynamic therapy, there is still a poor prognosis for cancer patients, since cancer cells have been detected at a distance up to 4 cm beyond the identifiable borders of the tumor and recurrent cancer usually develops adjacent to the resection borders. As there is evidence to suggest that is necessary to develop third-generation photosensitizers for precision photodynamic therapy, which can bind to targeted areas of difficult-to-reach microinvasion for cancer eradication, while preserving sensitive healthy tissues and improving patient outcomes. This Special Issue will be devoted to various aspects of photodynamic therapy; however, each of these aspects will oscillate around anticancer drug discovery and development. We welcome papers pertaining to the synthesis and applications of photosensitizers for photodynamic therapy, clinical trials with the use of photosensitizers, papers regarding the interactions of photosensitizers with drugs and vitamins, reviews and metanalyses, and original research. Precision photodynamic therapy, with the use of novel photosensitizers, represents a type of point source targeting. Ensuring precision in this therapy is important for killing cancer cells, and may help provide insights into treatment and diagnostics.
Prof. Dr. Dorota Bartusik-Aebisher
Prof. Dr. David Aebisher
Guest Editors
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Keywords
- cancer
- drug delivery
- magnetic resonance imaging
- diagnostics
- treatment
- photodynamic therapy
- diagnostics
- photosensitizers
- photomedicine
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