Catalytic Cascade Reactions
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: closed (10 October 2017) | Viewed by 11818
Special Issue Editor
Interests: organometallics; palladacycles; heterocycles; palladium-catalyzed reactions; multi-component reactions; sequential metal-catalyzed reactions; pot economy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, the drive to maximize the brevity of synthetic schemes came to the forefront of organic synthesis. The emergence of various cascade reactions, also referrred to as domino or tandem reactions, brought about major breakthroughs in this field. Cascade reactions create multiple carbon–carbon bonds in a single synthetic operation and rapidly achieve a significant increase in the molecular complexity. Cascade reactions that are performed under catalytic conditions are the most desirable from the standpoint of overall atom economy.
Strategic applications of cascade reactions with diverse mechanistic foundations (reactions with ionic, radical or metal-containing intermediates) in total synthesis delivered impressively short and efficient routes to highly complex organic structures.
The aims of this Special Issue is to highlight recent advances in the design, development and applications of catalytic cascade reactions to organic synthesis. Of special interest are catalytic asymmetric reactions, as well as protocols that could trigger stereo-divergent or regio-divergent pathways by a change in the features of the catalytic system.
Prof. Dr. Helena C. Malinakova
Guest Editor
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Keywords
- Step economy
- Carbon economy
- Cascade reactions
- Tandem reactions
- Domino reactions
- Asymmetric catalysis
- Transition metal-catalysis
- Organocatalysis
- Single-electron transfer
- Photocatalysis
- Stereo-divergent
- Regio-divergent
